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Increased numbers of interleukin-12-producing cells in human tuberculosis.

机译:人结核中产生白介素12的细胞数量增加。

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Numbers of interleukin-12 (IL-12) producing cells were quantitated in the peripheral blood of healthy donors and tuberculosis patients by the ELISPOT assay. We observed that (i) stimulation with mycobacteria increases numbers of IL-12 producers from healthy donors and (ii) tuberculosis patients have larger numbers of IL-12 producers than healthy donors. Our data emphasize the importance of Il-12 in immunity to tuberculosis.
机译:通过ELISPOT分析定量健康供体和肺结核患者外周血中产生白介素12(IL-12)的细胞数量。我们观察到(i)分枝杆菌刺激增加了健康供体的IL-12产生者的数量,并且(ii)肺结核患者的IL-12产生者的数量要多于健康供体。我们的数据强调了Il-12在结核病免疫中的重要性。

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