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首页> 外文期刊>Infection and immunity >Enteroaggregative Escherichia coli strains secrete a heat-labile toxin antigenically related to E. coli hemolysin.
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Enteroaggregative Escherichia coli strains secrete a heat-labile toxin antigenically related to E. coli hemolysin.

机译:肠聚合性大肠杆菌菌株分泌与大肠杆菌溶血素抗原相关的不耐热毒素。

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摘要

A protein toxin of approximately 120,000 Da secreted by nonhemolytic enteroaggregative Escherichia coli strains cross-reacted in Western blots (immunoblots) with antibodies raised against the C-terminal region of E. coli hemolysin. Treatment of HEp-2 cells with enteroaggregative E. coli or culture supernatants caused elevation of intracellular calcium and stimulated calcium-dependent protein phosphorylation.
机译:非溶血性肠聚集性大肠杆菌菌株分泌的大约120,000 Da的蛋白质毒素在Western印迹(免疫印迹)中与针对大肠杆菌溶血素C末端的抗体发生交叉反应。用肠聚合性大肠杆菌或培养上清液处理HEp-2细胞会引起细胞内钙离子升高,并刺激钙依赖性蛋白磷酸化。

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