Probiotics Reduce Enterohemorrhagic Escherichia coli O157:H7- and Enteropathogenic E. coli O127:H6-Induced Changes in Polarized T84 Epithelial Cell Monolayers by Reducing Bacterial Adhesion and Cytoskeletal Rearrangements

Philip M. Sherman; Kathene C. Johnson-Henry; Helen P. Yeung; Peter S. C. Ngo; Jacques Goulet; Thomas A. Tompkins

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Probiotics Reduce Enterohemorrhagic Escherichia coli O157:H7- and Enteropathogenic E. coli O127:H6-Induced Changes in Polarized T84 Epithelial Cell Monolayers by Reducing Bacterial Adhesion and Cytoskeletal Rearrangements

机译：益生菌可通过减少细菌粘附和细胞骨架重排减少肠出血性大肠杆菌O157：H7和肠致病性大肠杆菌O127：H6-诱导的极化T84上皮细胞单层的变化

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The aim of this study was to determine if probiotics reduce epithelial injury following exposure to Escherichia coli O157:H7 and E. coli O127:H6. The pretreatment of intestinal (T84) cells with lactic acid-producing bacteria reduced the pathogen-induced drop in transepithelial electrical resistance. These findings demonstrate that probiotics prevent epithelial injury induced by attaching-effacing bacteria.

机译：这项研究的目的是确定益生菌是否能减少暴露于大肠杆菌 O157：H7和 E后的上皮损伤。大肠杆菌O127：H6。用产生乳酸的细菌预处理肠道（T84）细胞可减少病原体引起的跨上皮电阻下降。这些发现表明，益生菌可防止因附着细菌引起的上皮损伤。 展开▼

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《Infection and immunity》 |2005年第8期|共6页

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Philip M. Sherman; Kathene C. Johnson-Henry; Helen P. Yeung; Peter S. C. Ngo; Jacques Goulet; Thomas A. Tompkins;
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中图分类医学免疫学;

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1. The enterohaemorrhagic Escherichia coli (serotype O157:H7) Tir molecule is not functionally interchangeable for its enteropathogenic E. coli (serotype O127:H6) homologue [J] . Brendan Kenny Cellular microbiology . 2001,第8期

机译：肠出血性大肠杆菌（血清型O157：H7）的Tir分子与其致肠病性大肠杆菌（血清型O127：H6）的同系物在功能上不可互换

2. EspM inhibits pedestal formation by enterohaemorrhagic Escherichia coli and enteropathogenic E. coli and disrupts the architecture of a polarized epithelial monolayer [J] . Simovitch M., Sason H., Cohen S., Cellular microbiology . 2010,第4期

机译：EspM抑制肠出血性大肠杆菌和肠致病性大肠杆菌的基座形成，并破坏极化的上皮单层的结构

3. A MinD mutant of enterohemorrhagic E. coli O157:H7 has reduced adherence to human epithelial cells. [J] . Parti R. P, Biswas D, Wang M, Microbial Pathogenesis . 2011,第5期

机译：肠出血性 E的MinD 突变体。大肠杆菌O157：H7减少了对人上皮细胞的粘附。

4. E. Coli bacterial foraging algorithm applied to pressure reducing valves control [C] . Ramirez-Llanos E., Quijano N. American Control Conference, 2009. ACC '09 . 2009

机译：E.大肠细菌觅食算法应用于减压阀控制

5. Happy beef: The development of beta-phenylethylamine as a novel nutrient treatment reducing bacterial cell count by Escherichia coli O157:H7 on beef meat. [D] . Lynnes, Ty Cordell. 2013

机译：快乐牛肉：β-苯乙胺作为一种新型营养处理技术的开发，可减少大肠杆菌O157：H7对牛肉的细菌细胞计数。

6. Probiotics Reduce Enterohemorrhagic Escherichia coli O157:H7- and Enteropathogenic E. coli O127:H6-Induced Changes in Polarized T84 Epithelial Cell Monolayers by Reducing Bacterial Adhesion and Cytoskeletal Rearrangements [O] . Philip M. Sherman, Kathene C. Johnson-Henry, Helen P. Yeung, 2005

机译：益生菌通过减少细菌粘附和细胞骨架重排减少肠出血性大肠杆菌O157：H7和肠致病性大肠杆菌O127：H6-诱导的极化T84上皮细胞单层的变化

7. Probiotics Reduce Enterohemorrhagic Escherichia coli O157:H7- and Enteropathogenic E. coli O127:H6-Induced Changes in Polarized T84 Epithelial Cell Monolayers by Reducing Bacterial Adhesion and Cytoskeletal Rearrangements [O] . Sherman, Philip M., Johnson-Henry, Kathene C., Yeung, Helen P., 2005

机译：益生菌通过减少细菌粘附和细胞骨架重排减少肠出血性大肠杆菌O157：H7和肠致病性大肠杆菌O127：H6诱导的极化T84上皮细胞单层的变化

1. CONTROL OF ENTEROHEMORRHAGIC E. COLI O157:H7 IN CATTLE BY PROBIOTIC BACTERIA [P] . 外国专利： KR100447903B1 . 2004-09-08

机译：益生菌控制牛的肠出血性大肠杆菌O157：H7

2. Control of enterohemorrhagic e. coli O157:H7 in cattle by probiotic bacteria [P] . 外国专利： AU735914B2 . 2001-07-19

机译：控制肠出血e。益生菌在牛中感染O157：H7大肠杆菌

3. . 157:7 CONTROL OF ENTEROHEMORRHAGIC E. COLI O157:H7 IN CATTLE BY PROBIOTIC BACTERIA [P] . 外国专利： KR20010022906A . 2001-03-26

机译：。 157：7通过益生菌控制牛的肠出血性大肠杆菌大肠杆菌O157：H7

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Probiotics Reduce Enterohemorrhagic Escherichia coli O157:H7- and Enteropathogenic E. coli O127:H6-Induced Changes in Polarized T84 Epithelial Cell Monolayers by Reducing Bacterial Adhesion and Cytoskeletal Rearrangements

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