首页> 外文期刊>International journal of infectious diseases : >Adult invasive pneumococcal disease in the Republic of Korea: Risk medical conditions and mortality stratified by age group
【24h】

Adult invasive pneumococcal disease in the Republic of Korea: Risk medical conditions and mortality stratified by age group

机译:大韩民国成人侵袭性肺炎球菌疾病:按年龄段分层的危险医疗条件和死亡率

获取原文
           

摘要

Objectives This study aimed to characterize the risk factors for mortality in adult patients with invasive pneumococcal disease (IPD) stratified by age groups, after implementation of the national immunization program of 23-valent polysaccharide vaccine (PPSV23) for those aged ≥65 years in the Republic of Korea (ROK). Methods Clinical data and pneumococcal isolates from adult patients with IPD (≥18 years of age) were collected prospectively from 20 hospitals through the nationwide surveillance program from March 2013 to October 2015. Results A total of 319 patients with IPD were enrolled. Median age was 69 years. Overall in-hospital mortality was 34.2%: 17.1% in those aged 18–49 years, 23.7% in those aged 50–64 years, 33.0% in those aged 65–74 years, and 51.0% in those aged ≥75 years ( p Conclusions This study suggests that vaccine-type IPD continues to place a substantial burden on older adults in the ROK, necessitating an effective vaccination strategy for those at higher risk.
机译:目的本研究旨在对年龄≥65岁的23岁多糖疫苗(PPSV23)实施国家免疫计划后,按年龄组对成年侵袭性肺炎球菌疾病(IPD)成年患者的死亡危险因素进行特征分析。大韩民国(ROK)。方法从2013年3月至2015年10月,通过全国性监测计划,从全国20家医院前瞻性收集IPD成人(≥18岁)患者的临床数据和肺炎球菌分离株。结果共纳入319例IPD患者。中位年龄为69岁。总体住院死亡率为34.2%:18-49岁的人群为17.1%,50-64岁的人群为23.7%,65-74岁的人群为33.0%,75岁以上的人群为51.0%(p结论该研究表明,疫苗型IPD继续给韩国老年人带来沉重负担,因此有必要为高危人群提供有效的疫苗接种策略。

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号