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首页> 外文期刊>International journal of infectious diseases : >Characteristics and factors associated with nosocomial pneumonia among patients undergoing continuous renal replacement therapy (CRRT): A case–control study
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Characteristics and factors associated with nosocomial pneumonia among patients undergoing continuous renal replacement therapy (CRRT): A case–control study

机译：连续性肾脏替代治疗（CRRT）患者的院内肺炎的特征和相关因素：一项病例对照研究

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Objectives Continuous renal replacement therapy (CRRT) is a specialized type of dialysis. However, the characteristics and factors associated with nosocomial pneumonia in patients undergoing CRRT have received little attention to date. Therefore, this study investigated the characteristics of and factors contributing to nosocomial pneumonia in patients receiving CRRT. Methods The clinical data of 1160 patients undergoing CRRT during the period January 2008 to December 2015 were analyzed retrospectively. Of these 1160 cases, 145 (12.5%) were included in the nosocomial pneumonia group, while 1015 were included in the control group. Results The primary pathogen in the 145 cases of nosocomial pneumonia in the CRRT patients was Staphylococcus aureus (58.57%); the morbidity rate was 12.5%. Multivariate logistic regression analysis revealed that age (odds ratio (OR) 2.209), initial curative time (OR 1.960), underlying diseases (OR 1.820), consciousness disorder (OR 1.616), organ failure (OR 2.154), the Acute Physiology and Chronic Health Evaluation II score (APACHE II) (OR 1.186), and the Charlson Comorbidity Index score (CCI) (OR 1.278) were risk factors for nosocomial pneumonia (all p Conclusions Results from this study indicate that by modifying risk factors, such as providing adequate nutrition, earlier treatment of underlying diseases, and controlling organ failure, the risks associated with nosocomial pneumonia may be reduced.
机译：目的连续肾脏替代疗法（CRRT）是一种特殊的透析方法。然而，迄今为止，接受CRRT的患者中与医院内肺炎相关的特征和因素很少受到关注。因此，本研究调查了接受CRRT的患者的院内肺炎的特征和因素。方法回顾性分析2008年1月至2015年12月收治的1160例CRRT患者的临床资料。在这1160例病例中，医院内肺炎包括145例（12.5％），而对照组则包括1015例。结果CRRT患者145例医院内肺炎的主要病原体为金黄色葡萄球菌（58.57％）。发病率为12.5％。多元logistic回归分析显示年龄（优势比（OR）2.209），初始治愈时间（OR 1.960），基础疾病（OR 1.820），意识障碍（OR 1.616），器官衰竭（OR 2.154），急性生理和慢性健康评估II评分（APACHE II）（OR 1.186）和查尔森合并症评分（CCI）（OR 1.278）是医院内肺炎的危险因素（所有p结论）这项研究的结果表明，通过改变危险因素，例如提供充足的营养，早期疾病的治疗以及控制器官衰竭，可以减少与医院内肺炎相关的风险。

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