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首页> 外文期刊>International journal of infectious diseases : >Successful treatment of avian-origin influenza A (H7N9) infection using convalescent plasma
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Successful treatment of avian-origin influenza A (H7N9) infection using convalescent plasma

机译：使用恢复性血浆成功治疗禽源性A型流感（H7N9）感染

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In January 2015, there was an outbreak of avian-origin influenza A (H7N9) virus in Zhejiang Province, China. A 45-year-old man was admitted to the First Affiliated Hospital of Zhejiang University with a high fever that had lasted 7 days, chills, and a cough with yellow sputum. Laboratory testing confirmed infection with the H7N9 virus, likely obtained from contact with poultry at a local live poultry market. A large dense shadow was apparent in the patient's left lung at the time of admission. Treatment with oseltamivir (75mg twice daily) did not improve the patient's condition. The decision was made to try using convalescent plasma to treat the infection. Convalescent plasma was administered 3 days after the patient was admitted to the hospital and led to a marked improvement. To our knowledge, this is the first report of the successful use of convalescent plasma to treat a case of H7N9 infection in China. These results suggest that the combination of convalescent plasma and antiviral drugs may be effective for the treatment of avian-origin H7N9 infection.
机译：2015年1月，中国浙江省爆发了一次禽源性甲型H7N9流感病毒。一名45岁的男子因持续7天的高烧，发冷和咳嗽伴黄痰入院到浙江大学第一附属医院。实验室测试证实了H7N9病毒的感染，很可能是通过在当地活禽市场与禽接触而获得的。入院时患者左肺有明显的大阴影。用奥司他韦（75mg每天两次）治疗并不能改善患者的病情。决定尝试使用恢复期血浆来治疗感染。患者入院3天后给予恢复血浆，导致明显改善。据我们所知，这是在中国成功使用恢复性血浆治疗H7N9感染病例的第一份报告。这些结果表明，恢复性血浆和抗病毒药物的组合可能有效治疗禽源性H7N9感染。

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