...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Investigative ophthalmology & visual science >Biomechanical Differences Between Femtosecond Lenticule Extraction (FLEx) and Small Incision Lenticule Extraction (SmILE) Tested by 2D-Extensometry in Ex Vivo Porcine Eyes
【24h】

Biomechanical Differences Between Femtosecond Lenticule Extraction (FLEx) and Small Incision Lenticule Extraction (SmILE) Tested by 2D-Extensometry in Ex Vivo Porcine Eyes

机译：在体外猪眼中通过二维引伸法测试飞秒小孔提取（FLEx）和小切口小孔提取（SmILE）之间的生物力学差异

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose: To evaluate the biomechanical stability of ex vivo porcine corneas after femtosecond lenticule extraction (FLEx) and small incision lenticule extraction (SmILE) refractive surgeries. Methods: Forty-five porcine eyes were equally divided into three groups: Groups 1 and 2 were treated with FLEx and SmILE procedure, respectively. Group 3 served as control. A refractive correction of a??14 diopters (D) with a 7-mm zone using either a 160-??m flap (FLEx) or a 160-??m cap (SmILE) was performed. For two-dimensional (2D) elastic and viscoelastic biomechanical characterization, two testing cycles (preconditioning stressa??strain curve from 1.27 to 12.5 N, stressa??relaxation at 12.5 N during 120 seconds) were conducted. Young's modulus and Prony constants were calculated. Results: At 0.8% of strain, FLEx (370 ?± 36 kPa) could resist a significantly lower stress than SmILE (392 ?± 19 kPa, P = 0.046) and the control group (402 ?± 30 kPa, P = 0.013). Also, FLEx (46.1 ?± 4.5 MPa) had a significantly lower Young's modulus than the control group (50.2 ?± 3.4 MPa, P = 0.008). The Young's modulus of SmILE (48.6 ?± 2.5 MPa) had values situated between untreated corneas and FLEx-treated corneas. When compared to untreated controls, the stress resistance decreased by 8.0% with FLEx and 2.5% with SmILE; Young's modulus decreased by 5.1% with FLEx and 1.04% with SmILE. With a cap-based procedure, both anterior cap and stromal bed carry the intraocular pressure, while in a flap-based procedure, only the stromal bed does. Conclusions: Compared to flap-based procedures like FLEx, the cap-based technique SmILE can be considered superior in terms of biomechanical stability, when measured experimentally in ex vivo porcine corneas.
机译：目的：评估飞秒小透镜摘除术（FEx）和小切口小透镜摘除术（SmILE）屈光手术后离体猪角膜的生物力学稳定性。方法：将45只猪眼平均分为三组：第1组和第2组分别用FLEx和SmILE程序治疗。第3组作为对照。使用160？m的襟翼（FLEx）或160？m的帽盖（SmILE）对7mm的a ?? 14屈光度（D）进行屈光矫正。为了进行二维（2D）弹性和粘弹性生物力学表征，进行了两个测试循环（从1.27到12.5 N的预处理应力-应变曲线，在120秒内12.5 N处的应力-松弛）。计算杨氏模量和Prony常数。结果：当应变为0.8％时，FLEx（370±±36 kPa）可以承受的应力明显低于SmILE（392±±19 kPa，P = 0.046）和对照组（402±±30 kPa，P = 0.013） 。另外，FLEx（46.1≤±4.5MPa）的杨氏模量显着低于对照组（50.2≤±3.4MPa，P ＝ 0.008）。 SmILE的杨氏模量（48.6Ω±2.5MPa）的值介于未处理的角膜和FLEx处理的角膜之间。与未处理的对照组相比，FLEx和SmILE的抗逆性分别降低了8.0％和2.5％。使用FLEx的杨氏模量下降5.1％，使用SmILE的杨氏模量下降1.04％。对于基于帽的手术，前帽和基质床均承担眼内压，而在基于皮瓣的手术中，仅基质床起作用。结论：与基于襟翼的手术如FLEx相比，基于帽的技术SmILE在离体猪角膜中进行实验测量时，在生物力学稳定性方面被认为是优越的。

著录项

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号