Enzootic Transmission of Yellow Fever Virus in Peru

J. Bryant; Heiman Wang; Cesar Cabezas; Gladys Ramirez; Douglas Watts; Kevin Russell; Alan Barrett

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Enzootic Transmission of Yellow Fever Virus in Peru

机译：秘鲁黄热病毒的昆虫传播

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The prevailing paradigm of yellow fever virus (YFV)ecology in South America is that of wandering epizootics.The virus is believed to move from place to place in epi-zootic waves involving monkeys and mosquitoes, ratherthan persistently circulating within particular locales. After alarge outbreak of YFV illness in Peru in 1995, we used phy-logenetic analyses of virus isolates to reexamine thehypothesis of virus movement. We sequenced a 670-nucleotide fragment of the prM/E gene region from 25Peruvian YFV samples collected from 1977 to 1999, anddelineated six clades representing the states(Departments) of Puno, Pasco, Junin, Ayacucho, SanMartin/Huanuco, and Cusco. The concurrent appearanceof at least four variants during the 1995 epidemic and thegenetic stability of separate virus lineages over time indi-cate that Peruvian YFV is locally maintained and circulatescontinuously in discrete foci of enzootic transmission

机译：在南美，黄热病病毒（YFV）生态学的流行范例是飘动的动物流行病。据信，这种病毒在涉及猴子和蚊子的动物流行病中从一个地方转移到另一个地方，而不是在特定区域内持续传播。在1995年秘鲁爆发大规模的YFV疾病后，我们使用了病毒分离株的系统学分析来重新检查病毒运动的假说。我们从1977年至1999年收集的25个秘鲁YFV样本中对prM / E基因区域的670个核苷酸片段进行了测序，描绘了代表普诺州，帕斯科州，朱宁州，阿亚库乔州，圣马丁/瓦努科州和库斯科州的六个进化枝。在1995年流行期间至少同时出现四个变种，以及各个病毒谱系随时间的遗传稳定性表明，秘鲁YFV是局部维持的，并在不连续的疫源性传播点中连续循环

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《Emerging Infectious Diseases》 |2003年第8期|共8页
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J. Bryant; Heiman Wang; Cesar Cabezas; Gladys Ramirez; Douglas Watts; Kevin Russell; Alan Barrett;
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1. Enzootic Transmission of Yellow Fever Virus, Venezuela (http://wwwnc.cdc.gov/eid/article/21/1/14-0814) [J] . Albert J Auguste, Philippe Lemey, Nicholas A Bergren, Emerging Infectious Diseases . 2015,第1期

机译：委内瑞拉黄热病毒的动物传播（http://wwwnc.cdc.gov/eid/article/21/1/14-1414）
2. Travel characteristics and yellow fever vaccine usage among US global TravEpiNet travelers visiting countries with risk of yellow fever virus transmission, 2009-2011 [J] . JentesE.S., HanP., GershmanM.D., The American Journal of Tropical Medicine and Hygiene . 2013,第5期

机译：2009-2011年，美国全球TravEpiNet旅行者前往有黄热病病毒传播危险国家的旅行者的旅行特征和黄热病疫苗的使用
3. Transmission Dynamics of Rift Valley Fever Virus: Effects of Live and Killed Vaccines on Epizootic Outbreaks and Enzootic Maintenance [J] . Farida Chamchod, Chris Cosner, R. Stephen Cantrell, Frontiers in Microbiology . 2015,第6期

机译：裂谷热病毒的传播动力学：活疫苗和杀伤疫苗对流行病爆发和动物维持的影响
4. VIRUS-LIKE PARTICLES (VLPs) AS A PLATFORM FOR THE DEVELOPMENT OF YELLOW FEVER AND ZIKA VIRUS VACCINE CANDIDATES [C] . Renata G. F. Alvim, Leda R. Castilho Conference on vaccine technology VI . 2018

机译：病毒样颗粒（VLP）作为开发黄热病和寨卡病毒疫苗候选人的平台
5. The Role of the Axl Receptor in Yellow Fever Virus Infection of Human Macrophages [D] . Oloke, Ajiboye Arinola. 2020

机译：AXL受体在黄热病病毒感染人巨噬细胞的作用
6. Enzootic Transmission of Yellow Fever Virus in Peru [O] . Juliet Bryant, Heiman Wang, Cesar Cabezas, 2003

机译：秘鲁黄热病毒的昆虫传播
7. Enzootic Transmission of Yellow Fever Virus in Peru [O] . Bryant, Juliet, Wang, Heiman, Cabezas, Cesar, 2003

机译：秘鲁黄热病毒的昆虫传播
8. Lymphocytes and Yellow Fever. II. Mechanisms Involved in the Transient Virus Refractory State Following Vaccination in Man with the 17-D Strain of Yellow Fever Virus [R] . Wheelock, E. F. 1974

机译：淋巴细胞和黄热病。 II。用17-D黄热病毒株接种人体疫苗后瞬时病毒难治状态的机制

Enzootic Transmission of Yellow Fever Virus in Peru

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