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Hantaviruses in Rodents and Humans, Inner Mongolia Autonomous Region, China

机译:内蒙古自治区啮齿动物和人类中的汉坦病毒

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Surveys were carried out in 2003–2006 to better un-derstand the epidemiology of hantaviruses in the Inner Mongolia Autonomous Region of China (Inner Mongolia). Hemorrhagic fever with renal syndrome (HFRS) was first reported in this region in 1955 and has been an important public health problem here since then. During 1955–2006, 8,309 persons with HFRS were reported in Inner Mongolia (average incidence rate 0.89/100,000), and 261 (3.14%) died. Before the 1990s, all HFRS cases occurred in north-eastern Inner Mongolia. Subsequently, HFRS cases were registered in central (1995) and western (1999) Inner Mon-golia. In this study, hantaviral antigens were identified in striped field mice (Apodemus agrarius) from northeastern Inner Mongolia and in Norway rats (Rattus norvegicus) from middle and western Inner Mongolia. Phylogenetic analysis of hantaviral genome sequences suggests that HFRS has been caused mainly by Hantaan virus in northeastern Inner Mongolia and by Seoul virus in central and western Inner Mongolia
机译:为了更好地了解中国内蒙古自治区(内蒙古)的汉坦病毒流行病学,于2003年至2006年进行了调查。肾综合征出血热(HFRS)最早于1955年在该地区报道,此后一直是该地区重要的公共卫生问题。在1955年至2006年期间,内蒙古报告了8309人患有HFRS(平均发病率为0.89 / 100,000),并且有261人(3.14%)死亡。在1990年代之前,所有HFRS病例都发生在内蒙古东北部。随后,在中部(1995年)和西部(1999年)内蒙古登记了HFRS案件。在这项研究中,在内蒙古东北部的条纹田鼠(Apodemus agrarius)和内蒙古中西部的挪威大鼠(Rattus norvegicus)中鉴定了汉坦病毒抗原。汉坦病毒基因组序列的系统发育分析表明,HFRS主要由内蒙古东北部的汉塔病毒和内蒙古中西部的汉城病毒引起

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