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首页> 外文期刊>Emerging Infectious Diseases >Itaya virus, a Novel Orthobunyavirus Associated with Human Febrile Illness, Peru (http://wwwnc.cdc.gov/eid/article/21/5/14-1368)
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Itaya virus, a Novel Orthobunyavirus Associated with Human Febrile Illness, Peru (http://wwwnc.cdc.gov/eid/article/21/5/14-1368)

机译:Itaya病毒,一种与人类高热疾病相关的新型正统病毒,http://wwwnc.cdc.gov/eid/article/21/5/14-1368

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摘要

Our genetic analyses of uncharacterized bunyaviruses isolated in Peru identified a possible reassortant virus containing small and large gene segment sequences closely related to the Caraparu virus and a medium gene segment sequence potentially derived from an unidentified group C orthobunyavirus. Neutralization tests confirmed serologic distinction among the newly identified virus and the prototype and Caraparu strains. This virus, named Itaya, was isolated in 1999 and 2006 from febrile patients in the cities of Iquitos and Yurimaguas in Peru. The geographic distance between the 2 cases suggests that the Itaya virus could be widely distributed throughout the Amazon basin in northeastern Peru. Identification of a new Orthobunyavirus species that causes febrile disease in humans reinforces the need to expand viral disease surveillance in tropical regions of South America.
机译:我们对在秘鲁分离出的未表征的布尼亚病毒的遗传分析确定了一种可能的重配病毒,其中包含与Caraparu病毒密切相关的大小基因片段序列,以及可能源自未鉴定的C型正支病毒的中等基因片段序列。中和测试证实了新鉴定的病毒与原型病毒和Caraparu毒株之间的血清学区别。该病毒名为Itaya,分别于1999年和2006年从秘鲁伊基托斯和尤里马瓜斯的发热患者中分离出来。这两个案例之间的地理距离表明,Itaya病毒可能广泛分布于秘鲁东北部的整个亚马逊河流域。对导致人类发烧性疾病的新正畸病毒的鉴定,加强了在南美热带地区扩大对病毒性疾病监测的需求。

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