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Pregnant Women Hospitalized with Chikungunya Virus Infection, Colombia, 2015

机译:2015年,哥伦比亚因基孔肯雅病毒感染住院的孕妇

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In 2015 in Colombia, 60 pregnant women were hospitalized with chikungunya virus infections confirmed by reverse transcription PCR. Nine of these women required admission to the intensive care unit because of sepsis with hypoperfusion and organ dysfunction; these women met the criteria for severe acute maternal morbidity. No deaths occurred. Fifteen women delivered during acute infection; some received tocolytics to delay delivery until after the febrile episode and prevent possible vertical transmission. As recommended by a pediatric neonatologist, 12 neonates were hospitalized to rule out vertical transmission; no clinical findings suggestive of neonatal chikungunya virus infection were observed. With 36 women (60%), follow-up was performed 1 year after acute viremia; 13 patients had arthralgia in > 2 joints (a relapse of infection). Despite disease severity, pregnant women with chikungunya should be treated in high-complexity obstetric units to rule out adverse outcomes. These women should also be followed up to treat potential relapses.
机译:2015年,在哥伦比亚,有60名孕妇因逆转录PCR确诊后感染了基孔肯雅病毒感染。这些妇女中有9名由于败血症伴有灌注不足和器官功能障碍而需要进入重症监护病房。这些妇女符合严重的急性孕产妇发病标准。没有死亡发生。 15名妇女在急性感染期间分娩;一些人接受了生育抑制剂以延迟分娩直到高热发作之后,并防止可能的垂直传播。根据儿科新生儿科医生的建议,有12名新生儿入院以排除垂直传播。没有发现提示新生儿基孔肯雅病毒感染的临床发现。有36名妇女(60%)在急性病毒血症后1年进行了随访。 13例关节> 2个关节痛(感染复发)。尽管疾病严重,患有基孔肯雅热的孕妇应在高复杂性产科治疗,以排除不良后果。这些妇女也应接受随访以治疗潜在的复发。

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