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Passive Antibody Administration (Immediate Immunity) as a Specific Defense Against Biological Weapons

机译：被动抗体管理（立即免疫）作为对生物武器的特殊防御

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The potential threat of biological warfare with a specific agent is proportional to the susceptibility of thepopulation to that agent. Preventing disease after exposure to a biological agent is partially a function ofthe immunity of the exposed individual. The only available countermeasure that can provide immediateimmunity against a biological agent is passive antibody. Unlike vaccines, which require time to induce pro-tective immunity and depend on the host's ability to mount an immune response, passive antibody can the-oretically confer protection regardless of the immune status of the host. Passive antibody therapy hassubstantial advantages over antimicrobial agents and other measures for postexposure prophylaxis,including low toxicity and high specific activity. Specific antibodies are active against the major agents ofbioterrorism, including anthrax, smallpox, botulinum toxin, tularemia, and plague. This article proposes abiological defense initiative based on developing, producing, and stockpiling specific antibody reagentsthat can be used to protect the population against biological warfare threats
机译：使用特定试剂对生物战的潜在威胁与人口对该试剂的敏感性成正比。接触生物制剂后预防疾病在一定程度上取决于所接触个体的免疫力。可以提供针对生物制剂的立即免疫的唯一可用对策是被动抗体。与疫苗需要时间来诱导保护性免疫并取决于宿主发出免疫应答的能力不同，被动抗体可以从理论上讲提供保护，而与宿主的免疫状态无关。被动抗体疗法相对于抗菌剂和其他预防接触后措施具有实质性优势，包括低毒性和高比活性。特异性抗体对主要的生物恐怖分子具有活性，包括炭疽，天花，肉毒杆菌毒素，妥拉血病和鼠疫。本文基于开发，生产和储存可用于保护人群免受生物战威胁的特定抗体试剂的生物多样性防御计划

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