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Leishmania (Leishmania) amazonenis Infection, Suriname

机译：利什曼原虫（Leishmania）amazonenis感染，苏里南

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To the Editor: A 17-year-old man was seen at the Dermatology Service in Paramaribo (Suriname) with a skin condition that he had had since he was 5 years of age. The condition consist-ed of multiple cutaneous ulcerations, nodules, and fi brotic plaques dissemi-nated on his face, limbs, and trunk, and subcutaneous nodules on lymph-draining tracts on his hands, arms, and legs (online Appendix Figure, panel A, available from www.cdc.gov/EID/content/14/5/857-appG.htm). He had lived his entire life in an inland village, located at Brokopondo Lake (central-eastern Suriname); he had never trav-eled outside the country. The diagno-sis of cutaneous leishmaniasis (CL, a parasitic disease caused by the proto-zoa Leishmania) was presumed. The patient received pentamidine therapy in 1997, 1998, and 2005, but without sustained clinical effect. Rapid screen-ing tests for HIV were negative (De-termine [Abbott Laboratories, Tokyo, Japan] and Unigold [Trinity Biotech, Co. Wicklow, Ireland]). In 2006, the diagnosis of CL was confi rmed with histopathology, culture, and PCR. The parasite was identifi ed by a PCR restriction fragment length polymor-phism method on the small subunit–internal transcribed spacer genes (1) and by multilocus enzyme electropho-resis at the National Reference Center of Leishmania (Montpellier, France).
机译：致编辑：一名17岁男子在帕拉马里博（苏里南）的皮肤病服务处被发现，他的皮肤状况自5岁起就一直存在。该疾病包括多发性皮肤溃疡，结节和在其面部，四肢和躯干散布的纤维化斑块，以及手，臂和腿的淋巴引流道上的皮下结节（在线附录图，面板） A，网址为www.cdc.gov/EID/content/14/5/857-appG.htm）。他一生都住在布罗科蓬多湖（苏里南中东部）的内陆村庄。他从未出国旅行。假定诊断为皮肤利什曼病（CL，由原虫利什曼原虫引起的寄生虫病）。该患者在1997年，1998年和2005年接受喷他idine治疗，但没有持续的临床效果。对HIV的快速筛查测试为阴性（确定[Determine [Abbott Laboratories，东京，日本]和Unigold [Trinity Biotech，Co。Wicklow，爱尔兰]）。 2006年，CL的诊断通过组织病理学，培养和PCR确诊。寄生虫通过在小亚基内部转录的间隔基因上的PCR限制性片段长度多态性方法（1）和利什曼原虫国家参考中心（法国蒙彼利埃）的多位酶电泳鉴定。

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