Integrating Host Genomics with Surveillance for Invasive Bacterial Diseases

D. C. Crawford; Shanta M Zimmer; Craig A Morin; Nancy E Messonnier; Ruth Lynfi eld; Qian Yi; Cynthia Shephard; Michelle Wong; Mark J Rieder; Robert J Livingston; Deborah A Nickerson; Cynthia G Whitney; Jairam Lingappa

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Integrating Host Genomics with Surveillance for Invasive Bacterial Diseases

机译：将宿主基因组学与监测相结合，以应对细菌入侵性疾病

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We tested the feasibility of linking Active Bacterial Core surveillance, a prospective, population-based surveillance system for invasive bacterial disease, to a newborn dried blood spot (nDBS) repository. Using nDBS specimens, we resequenced CD46, putative host gene receptor for Neis-seria meningitidis, and identifi ed variants associated with susceptibility to this disease

机译：我们测试了将主动细菌核心监视（一种针对人群的侵入性细菌疾病监视系统）与新生儿干血斑（nDBS）存储库相链接的可行性。使用nDBS标本，我们对CD46，脑膜炎奈瑟氏菌的假定宿主基因受体进行了重测序，并确定了与该疾病易感性相关的变异体

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《Emerging Infectious Diseases》 |2008年第7期|共3页
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D. C. Crawford; Shanta M Zimmer; Craig A Morin; Nancy E Messonnier; Ruth Lynfi eld; Qian Yi; Cynthia Shephard; Michelle Wong; Mark J Rieder; Robert J Livingston; Deborah A Nickerson; Cynthia G Whitney; Jairam Lingappa;
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中图分类传染病;
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1. Integration of enteric fever surveillance into the WHO-coordinated Invasive Bacterial-Vaccine Preventable Diseases (IB-VPD) platform: A low cost approach to track an increasingly important disease [J] . Senjuti Saha, Maksuda Islam, Mohammad J. Uddin, PLOS Neglected Tropical Diseases . 2017,第10期

机译：将肠热监测整合到WHO协调的侵袭性细菌疫苗可预防疾病（IB-VPD）平台中：一种跟踪日益重要的疾病的低成本方法
2. Pediatric Bacterial Meningitis Surveillance in the World Health Organization African Region Using the Invasive Bacterial Vaccine-Preventable Disease Surveillance Network, 2011-2016 [J] . Mwenda Jason M., Soda Elizabeth, Weldegebriel Goitom, Clinical infectious diseases . 2019,第Suppla2期

机译：使用侵袭性细菌疫苗可预防的疾病监测网络，对世界卫生组织非洲地区的儿科细菌脑膜炎监测，2011-2016
3. A systematic review and critical evaluation of invasive Haemophilus influenzae type B disease burden studies in Asia from the last decade: lessons learned for invasive bacterial disease surveillance. [J] . Shetty S, Cohen AL, Edmond K, The Pediatric infectious disease journal . 2010,第7期

机译：对过去十年来亚洲的侵入性B型流感嗜血杆菌的疾病负担研究的系统评价和严格评估：侵入性细菌性疾病监测的经验教训。
4. Biostatistics Meets Bioinformatics in Integrating Information from Highdimensional Heterogeneous Genomic Data: Two Examples from Rare Genetic Diseases and Infectious Diseases [C] . Clelia Di Serio, Danilo Pellin, Alessandro Ambrosi, International meeting on computational intelligence methods for bioinformatics and biostatistics . 2012

机译：生物统计学在整合来自高维异构基因组数据的信息方面遇到了生物信息学：来自罕见遗传病和传染病的两个例子
5. An examination of exposure and risk factors for viral, bacterial and parasitic diseases among febrile patients: A surveillance project in Kilombero, Tanzania. [D] . Hercik, Christine A. 2016

机译：高热患者中病毒，细菌和寄生虫病的暴露和危险因素检查：坦桑尼亚Kilombero的监视项目。
6. Integrating Host Genomics with Surveillance for Invasive Bacterial Diseases [O] . Dana C. Crawford, Shanta M. Zimmer, Craig A. Morin, 2008

机译：将宿主基因组学与监测相结合以应对细菌入侵性疾病
7. Integrating Host Genomics with Surveillance for Invasive Bacterial Diseases [O] . Crawford, Dana C., Zimmer, Shanta M., Morin, Craig A., 2008

机译：将宿主基因组学与监测相结合，以应对细菌入侵性疾病

Integrating Host Genomics with Surveillance for Invasive Bacterial Diseases

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