583 POSTER mTORC1 inhibition with rapamycin leads to activation of P13K/AKT signalling via an mTORC2 dependent mechanism in melanoma cells

J.Werzowa; B.Pratscher; D.Cejka; H.Pehamberger; V.Wacheck

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583 POSTER mTORC1 inhibition with rapamycin leads to activation of P13K/AKT signalling via an mTORC2 dependent mechanism in melanoma cells

机译：雷帕霉素对583 POSTER mTORC1的抑制作用通过黑色素瘤细胞中的mTORC2依赖性机制激活P13K / AKT信号传导

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来源
《European Journal of Cancer Supplements》 |2006年第12期|共2页
作者
J.Werzowa; B.Pratscher; D.Cejka; H.Pehamberger; V.Wacheck;
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中图分类肿瘤学;
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1. Inhibition of mTORC1 by SU6656, the Selective Src Kinase Inhibitor, Is Not Accompanied by Activation of Akt/PKB Signalling in Melanoma Cells [J] . L. Ondru?ová, J. Réda, P. ?áková, Folia biologica . 2013,第4期

机译：SU6656（选择性Src激酶抑制剂）对mTORC1的抑制作用与黑素瘤细胞中Akt / PKB信号的激活无关
2. Inhibition of mTORC1 by SU6656, the Selective Src Kinase Inhibitor, Is Not Accompanied by Activation of Akt/PKB Signalling in Melanoma Cells [J] . L. Ondru?ˇov?ˇ, J. R??da, P. ???ˇkov?ˇ, Folia biologica . 1999,第4期

机译：SU6656（选择性Src激酶抑制剂）对mTORC1的抑制作用与黑素瘤细胞中Akt / PKB信号的激活无关
3. Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies. [J] . Gupta M, Hendrickson AE, Yun SS, Blood: The Journal of the American Society of Hematology . 2012,第2期

机译：双重mTORC1 / mTORC2抑制作用可减少Akt激活并诱导淋巴恶性肿瘤中Puma依赖性凋亡。
4. Cationic polystyrene nanosphere induces autophagy through inhibition of the Akt/mTOR and activation of the AMPK signaling pathways in macrophage and epithelial cells [C] . Hui-Wen Chiu, Tian Xia, Jui-Chen Tsai, Annual NSTI nanotechnology conference and expo . 2013

机译：阳离子聚苯乙烯纳米球通过抑制Akt / mTOR和激活巨噬细胞和上皮细胞中的AMPK信号通路来诱导自噬
5. Signaling mechanism by which thromboxane receptor activation modulates interleukin-1[beta]-induced monocyte adhesion and nuclear factor [kappa]B-dependent gene expression in vascular smooth muscle cells [D] . Bayat, Hossein 2008

机译：血栓烷受体激活调节血管平滑肌细胞中白介素-1β诱导的单核细胞粘附和核因子κB依赖性基因表达的信号传导机制
6. Mechanistic Target of Rapamycin Complex 1 (mTORC1) and mTORC2 as Key Signaling Intermediates in Mesenchymal Cell Activation [O] . Natalie M. Walker, Elizabeth A. Belloli, Linda Stuckey, 2016

机译：雷帕霉素复合物1（mTORC1）和mTORC2的机制目标作为间充质细胞激活中的关键信号传导中间体。
7. mTORC1 inhibition with rapamycin or LY294002 alone but not in combination leads to AKT phosphorylation via mTORC2 in melanoma cells [O] . 2007

机译：黑色素瘤细胞单独使用雷帕霉素或LY294002抑制mTORC1，但不联合使用会导致AKT通过mTORC2磷酸化

583 POSTER mTORC1 inhibition with rapamycin leads to activation of P13K/AKT signalling via an mTORC2 dependent mechanism in melanoma cells

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