首页> 外文期刊>Molecular and Cellular Biology >Sequence and structure of the Drosophila melanogaster ovarian tumor gene and generation of an antibody specific for the ovarian tumor protein.
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Sequence and structure of the Drosophila melanogaster ovarian tumor gene and generation of an antibody specific for the ovarian tumor protein.

机译:果蝇果蝇卵巢肿瘤基因的序列和结构以及对卵巢肿瘤蛋白特异的抗体的产生。

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摘要

Sequencing cDNA and genomic DNA from the ovarian tumor gene revealed a gene with seven introns spanning 4.5 kilobases. The proline-rich, hydrophilic otu protein is novel. An antibody prepared to a beta-gal-otu fusion protein recognized a 110-kilodalton ovarian protein which was altered in the ovaries of otu gene mutants.
机译:从卵巢肿瘤基因中测序cDNA和基因组DNA揭示了一个具有7个内含子的基因,这些内含子跨越4.5千个碱基。富含脯氨酸的亲水性otu蛋白是新颖的。针对β-gal-otu融合蛋白制备的抗体识别110千达尔顿的卵巢蛋白,该蛋白在otu基因突变体的卵巢中发生了改变。

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