...
首页> 外文期刊>Molecular and Cellular Biology >Pip92: a short-lived, growth factor-inducible protein in BALB/c 3T3 and PC12 cells.
【24h】

Pip92: a short-lived, growth factor-inducible protein in BALB/c 3T3 and PC12 cells.

机译:Pip92:BALB / c 3T3和PC12细胞中一种短寿命的,生长因子诱导性蛋白。

获取原文
           

摘要

pip92 is a cellular immediate-early gene inducible by serum growth factors in fibroblasts. It is also induced in the rat pheochromocytoma cell line PC12 by agents that cause proliferation, neuronal differentiation, and membrane depolarization. We show that the pip92-encoded polypeptide is a proline-rich protein of 221 amino acids, has an extremely short half-life, and is localized in the cytoplasm. We hypothesize that Pip92 plays a role in mediating the cellular responses to a variety of extracellular signals.
机译:pip92是可被成纤维细胞中的血清生长因子诱导的细胞早期基因。它也通过引起增殖,神经元分化和膜去极化的试剂在大鼠嗜铬细胞瘤细胞系PC12中诱导。我们表明,pip92编码的多肽是富含脯氨酸的221个氨基酸的蛋白质,具有极短的半衰期,并且位于细胞质中。我们假设Pip92在介导细胞对多种细胞外信号的反应中发挥作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号