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Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells.

机译:DNA破坏剂在中国仓鼠卵巢细胞中诱导β-聚合酶mRNA的表达。

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摘要

Only a few of the genes involved in DNA repair in mammalian cells have been isolated, and induction of a DNA repair gene in response to DNA damage has not yet been established. DNA polymerase beta (beta-polymerase) appears to have a synthetic role in DNA repair after certain types of DNA damage. Here we show that the level of beta-polymerase mRNA is increased in CHO cells after treatment with several DNA-damaging agents.
机译:仅分离了哺乳动物细胞中涉及DNA修复的几个基因,并且尚未确定响应DNA损伤的DNA修复基因的诱导。 DNA聚合酶beta(β-聚合酶)似乎在某些类型的DNA损伤后在DNA修复中具有合成作用。在这里,我们显示在用几种DNA损伤剂处理后,CHO细胞中β-聚合酶mRNA的水平增加了。

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