Species-specific lens activation of the thymidine kinase promoter by a single copy of the mouse alpha A-CRYBP1 site and loss of tissue specificity by multimerization.

C M Sax; J F Klement; J Piatigorsky

首页> 外文期刊>Molecular and Cellular Biology >Species-specific lens activation of the thymidine kinase promoter by a single copy of the mouse alpha A-CRYBP1 site and loss of tissue specificity by multimerization.

【24h】

Species-specific lens activation of the thymidine kinase promoter by a single copy of the mouse alpha A-CRYBP1 site and loss of tissue specificity by multimerization.

机译：小鼠αA-CRYBP1位点的单个拷贝对胸苷激酶启动子的物种特异性晶状体激活，以及通过多聚作用丧失组织特异性。

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

One copy of the mouse alpha A-crystallin gene alpha A-CRYBP1 site activated the thymidine kinase (tk) promoter in a mouse lens epithelial cell line but not in primary chicken lens cells; multiple copies further activated the tk promoter and extended expression to fibroblasts, B cells, and chicken lens cultures. The loss of lens specificity by multimerization may place selective constraints on the number of alpha A-CRYBP1 sites in the alpha A-crystallin promoter.

机译：小鼠αA-晶状蛋白基因αA-CRYBP1位点的一个副本激活了小鼠晶状体上皮细胞系中的胸苷激酶（tk）启动子，但未激活原代鸡晶状体细胞。多拷贝进一步激活了tk启动子，并将其表达延伸至成纤维细胞，B细胞和鸡晶状体培养物。通过多聚作用丧失晶状体特异性可能会对αA-晶状蛋白启动子中αA-CRYBP1位点的数量产生选择性限制。

著录项

来源
《Molecular and Cellular Biology》 |1990年第12期|共4页
作者
C M Sax; J F Klement; J Piatigorsky;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类细胞生物学;
关键词

相似文献

外文文献
中文文献
专利

1. Transfection of mouse fibroblast cells with a promoterless herpes simplex virus thymidine kinase gene: number of integrated gene copies and structure of single and amplified gene sequences. [J] . W Pülm, R Knippers Molecular and Cellular Biology . 1985,第2期

机译：用无启动子单纯疱疹病毒胸苷激酶基因转染小鼠成纤维细胞：整合的基因拷贝数以及单个和扩增基因序列的结构。
2. AP2alpha and AP2gamma: a comparison of binding site specificity and trans-activation of the estrogen receptor promoter and single site promoter constructs. [J] . McPherson LA, Weigel RJ Nucleic Acids Research . 1999,第20期

机译：AP2alpha和AP2gamma：雌激素受体启动子和单位点启动子构建体的结合位点特异性和反式激活的比较。
3. Promoter domains required for expression of plasmid-borne copies of the herpes simplex virus thymidine kinase gene in virus-infected mouse fibroblasts and microinjected frog oocytes. [J] . S P Eisenberg, D M Coen, S L McKnight Molecular and Cellular Biology . 1985,第8期

机译：在病毒感染的小鼠成纤维细胞和显微注射的青蛙卵母细胞中表达单纯疱疹病毒胸苷激酶基因的质粒携带拷贝所需的启动子结构域。
4. Quantifying the Site-specific Stability of Gold Nanoparticles in Mouse Tissues [C] . S.Gokhan Elci, Bo Yan, Sung Tae Kim, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：量化小鼠组织中金纳米粒子的位点特异性稳定性
5. Effects of specific conjugated linoleic acid (CLA) isomers on insulin resistance, and skeletal muscle AMP-activated protein kinase-alpha (AMPK-alpha) in fa/fa and lean Zucker rats. [D] . Diakiw, Robert Peter. 2006

机译：fa / fa和lean Zucker大鼠中特定共轭亚油酸（CLA）异构体对胰岛素抵抗和骨骼肌AMP激活的蛋白激酶-α（AMPK-α）的影响。
6. Species-specific lens activation of the thymidine kinase promoter by a single copy of the mouse alpha A-CRYBP1 site and loss of tissue specificity by multimerization. [O] . C M Sax, J F Klement, J Piatigorsky 1990

机译：小鼠αA-CRYBP1位点的单个拷贝对胸苷激酶启动子的物种特异性晶状体激活以及通过多聚作用丧失组织特异性。
7. Species-specific lens activation of the thymidine kinase promoter by a single copy of the mouse alpha A-CRYBP1 site and loss of tissue specificity by multimerization. [O] . Sax, C M, Klement, J F, Piatigorsky, J 1990

机译：小鼠αA-CRYBP1位点的单个拷贝对胸苷激酶启动子的物种特异性晶状体激活，以及通过多聚作用丧失组织特异性。

Species-specific lens activation of the thymidine kinase promoter by a single copy of the mouse alpha A-CRYBP1 site and loss of tissue specificity by multimerization.

摘要

著录项

相似文献

相关主题

期刊订阅