Differential regulation of the two genes encoding Saccharomyces cerevisiae cytochrome c oxidase subunit V by heme and the HAP2 and REO1 genes.

C E Trueblood; R M Wright; R O Poyton

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Differential regulation of the two genes encoding Saccharomyces cerevisiae cytochrome c oxidase subunit V by heme and the HAP2 and REO1 genes.

机译：血红素与HAP2和REO1基因对啤酒糖酵母细胞色素C氧化酶亚基V编码的两个基因的差异调节。

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In Saccharomyces cerevisiae, the COX5a and COX5b genes encode two forms of cytochrome c oxidase subunit V, Va and Vb. We report here that heme increases COX5a expression and decreases COX5b expression and that the HAP2 and REO1 genes are involved in positive regulation of COX5a and negative regulation of COX5b, respectively. Heme regulation of COX5a and COX5b may dictate which subunit V isoform is available for assembly into cytochrome c oxidase under conditions of high- and low-oxygen tension.

机译：在酿酒酵母中，COX5a和COX5b基因编码两种形式的细胞色素c氧化酶亚基V，Va和Vb。我们在这里报告血红素增加COX5a表达和减少COX5b表达，并且HAP2和REO1基因分别参与COX5a的正调控和COX5b的负调控。 COX5a和COX5b的血红素调节可能决定了在高和低氧张力条件下哪个亚基V亚型可用于组装成细胞色素c氧化酶。

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《Molecular and Cellular Biology》 |1988年第10期|共4页
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C E Trueblood; R M Wright; R O Poyton;
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中图分类细胞生物学;
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1. Nucleotide sequence of the gene encoding cytochrome c oxidase subunit VII from Saccharomyces cerevisiae [J] . Nucleic acids research . 1990,第6期

机译：酿酒酵母细胞色素c氧化酶亚基VII编码基因的核苷酸序列
2. Nucleotide sequence of the gene encoding cytochrome c oxidase subunit VII from Saccharomyces cerevisiae [J] . Nucleic acids research . 1990,第6期

机译：酿酒酵母细胞色素c氧化酶亚基VII编码基因的核苷酸序列
3. PET111, a Saccharomyces cerevisiae Nuclear Gene Required for Translation of the Mitochondrial mRNA Encoding Cytochrome c Oxidase Subunit II [J] . Candace G. Poutre, Thomas D. Fox Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 1987,第4期

机译：PET111，啤酒酵母的核基因，用于翻译编码细胞色素c氧化酶亚基II的线粒体mRNA
4. Tuning Heme Functionality: The Cases of Cytochrome c Oxidase and Myoglobin Oxidation [C] . Vangelis Daskalakis, Stavros C. Farantos, Constantinos Varotsis International conference on computational science and its applications . 2012

机译：调节血红素功能：细胞色素c氧化酶和肌红蛋白氧化的情况
5. Isolation and characterization of the nuclear gene and gene product of COX12, the gene encoding subunit Vlb of cytochrome c oxidase of Saccharomyces cerevisiae. [D] . LaMarche, Arthur Edward P. 1995

机译：啤酒酵母细胞色素C氧化酶Vlb亚基编码基因COX12的核基因和基因产物的分离与鉴定。
6. Differential regulation of the two genes encoding Saccharomyces cerevisiae cytochrome c oxidase subunit V by heme and the HAP2 and REO1 genes. [O] . C E Trueblood, R M Wright, R O Poyton 1988

机译：血红素与HAP2和REO1基因对啤酒糖酵母细胞色素C氧化酶亚基V编码的两个基因的差异调节。
7. Differential regulation of the two genes encoding Saccharomyces cerevisiae cytochrome c oxidase subunit V by heme and the HAP2 and REO1 genes. [O] . Trueblood, C E, Wright, R M, Poyton, R O 1988

机译：血红素与HAP2和REO1基因对啤酒糖酵母细胞色素C氧化酶亚基V编码的两个基因的差异调节。

Differential regulation of the two genes encoding Saccharomyces cerevisiae cytochrome c oxidase subunit V by heme and the HAP2 and REO1 genes.

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