The DAL81 gene product is required for induced expression of two differently regulated nitrogen catabolic genes in Saccharomyces cerevisiae.

P A Bricmont; J R Daugherty; T G Cooper

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The DAL81 gene product is required for induced expression of two differently regulated nitrogen catabolic genes in Saccharomyces cerevisiae.

机译：DAL81基因产物是在啤酒酵母中诱导表达两个不同调控的氮分解代谢基因所必需的。

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We demonstrate that the DAL81 gene, previously thought to be specifically required for induced expression of the allantoin pathway genes in Saccharomyces cerevisiae, functions in a more global manner. The data presented show it to be required for utilization of 4-aminobutyrate as a nitrogen source and for 4-aminobutyrate-induced increases in the steady-state levels of UGA1 mRNA. The DAL81 gene encodes a 970-amino-acid protein containing sequences homologous to the Zn(II)2Cys6 motif and two stretches of polyglutamine residues. Deletion of sequences homologous to the Zn(II)2Cys6 motif did not result in a detectable loss of function. On the other hand, loss of one of the polyglutamine stretches, but not the other, resulted in a 50% loss of DAL81 function.

机译：我们证明，DAL81基因，以前认为是酿酒酵母中尿囊素途径基因的诱导表达特别需要的，它以更全局的方式起作用。所提供的数据表明，它需要利用4-氨基丁酸酯作为氮源以及4-氨基丁酸酯诱导的UGA1 mRNA稳态水平上的增加。 DAL81基因编码一个970个氨基酸的蛋白质，该蛋白质包含与Zn（II）2Cys6基序同源的序列和两个延伸的聚谷氨酰胺残基。删除与Zn（II）2Cys6基序同源的序列不会导致可检测的功能丧失。另一方面，失去一个聚谷氨酰胺延伸段，但没有另一个，导致DAL81功能丧失50％。

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《Molecular and Cellular Biology》 |1991年第2期|共6页
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P A Bricmont; J R Daugherty; T G Cooper;
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中图分类细胞生物学;
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1. The URE2 protein regulates nitrogen catabolic gene expression through the GATAA-containing UASNTR element in Saccharomyces cerevisiae. [J] . J A Coffman, H M el Berry, T G Cooper Journal of bacteriology . 1994,第24期

机译：URE2蛋白通过酿酒酵母中含GATAA的UASNTR元件调节氮分解代谢基因的表达。
2. The URE2 protein regulates nitrogen catabolic gene expression through the GATAA-containing UASNTR element in Saccharomyces cerevisiae. [J] . J A Coffman, H M el Berry, T G Cooper Journal of bacteriology . 1994,第24期

机译：URE2蛋白通过酿酒酵母中含GATAA的UASNTR元件调节氮分解代谢基因的表达。
3. Regulatory circuit for responses of nitrogen catabolic gene expression to the GLN3 and DAL80 proteins and nitrogen catabolite repression in Saccharomyces cerevisiae. [J] . J R Daugherty, R Rai, H M el Berry, Journal of bacteriology . 1993,第1期

机译：酿酒酵母中氮分解代谢基因表达对GLN3和DAL80蛋白的响应和氮分解代谢物阻遏的调控回路。
4. Inducing dehydration tolerance in rice by regulated expression of genes for transcription factors [C] . S.J. Oh, E.H. Kim, S.Y. Kim, International Rice Genetics Symposium . 2008

机译：通过调节转录因子的基因表达诱导水稻脱水耐受性
5. RSF1 and RSF2, nuclear genes encoding proteins required for respiratory growth and mitochondrial DNA maintenance in Saccharomyces cerevisiae. [D] . Lu, Lin. 2003

机译：RSF1和RSF2是编码酿酒酵母中呼吸生长和线粒体DNA维持所需的蛋白质的核基因。
6. The DAL81 gene product is required for induced expression of two differently regulated nitrogen catabolic genes in Saccharomyces cerevisiae. [O] . P A Bricmont, J R Daugherty, T G Cooper 1991

机译：DAL81基因产物是在啤酒酵母中诱导表达两个不同调控的氮分解代谢基因所必需的。
7. The DAL81 gene product is required for induced expression of two differently regulated nitrogen catabolic genes in Saccharomyces cerevisiae. [O] . Bricmont, P A, Daugherty, J R, Cooper, T G 1991

机译：DAL81基因产物是在啤酒酵母中诱导表达两个不同调控的氮分解代谢基因所必需的。

The DAL81 gene product is required for induced expression of two differently regulated nitrogen catabolic genes in Saccharomyces cerevisiae.

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