Stimulation of sea urchin H2B histone gene transcription by a chromatin-associated protein fraction depends on gene sequences downstream of the transcription start site.

J Mous; H Stunnenberg; O Georgiev; M L Birnstiel

首页> 外文期刊>Molecular and Cellular Biology >Stimulation of sea urchin H2B histone gene transcription by a chromatin-associated protein fraction depends on gene sequences downstream of the transcription start site.

【24h】

Stimulation of sea urchin H2B histone gene transcription by a chromatin-associated protein fraction depends on gene sequences downstream of the transcription start site.

机译：染色质相关蛋白部分刺激海胆H2B组蛋白基因转录取决于转录起始位点下游的基因序列。

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

We isolated a chromosomal protein fraction derived from chromatin of sea urchin embryos which specifically stimulated the expression of the histone H2B gene by a factor of 5- to 10-fold when the complete sea urchin histone gene repeat h22 was injected in Xenopus laevis oocyte nuclei. Gene manipulation experiments revealed the existence of two different target sites in the H2B gene which appear to mediate the response to injection of the stimulatory sea urchin chromatin-associated proteins; both are located downstream of the transcription initiation site. The first sequence element which is shown to be implicated is within, or at least includes, the H2B 5' untranslated leader sequence between nucleotides 11 and 76. The second element resides within an H2B DNA segment located near the 3' end of the gene, extending from 90 base pairs upstream of the mRNA 3' terminus to 140 base pairs in the spacer sequences downstream.

机译：我们分离了海胆胚胎染色质衍生的染色体蛋白部分，当将完整的海胆组蛋白基因重复序列h22注入非洲爪蟾卵母细胞核中时，该蛋白特异性刺激组蛋白H2B基因的表达达5至10倍。基因操纵实验表明，H2B基因中存在两个不同的靶位点，它们似乎介导了注射刺激性海胆染色质相关蛋白的反应。两者都位于转录起始位点的下游。显示为牵连的第一序列元件在核苷酸11和76之间的H2B 5'非翻译前导序列之内，或至少包括该序列。第二元件位于基因3'端附近的H2B DNA区段内，从mRNA 3'末端上游的90个碱基对延伸到下游间隔区序列的140个碱基对。

著录项

来源
《Molecular and Cellular Biology》 |1985年第10期|共6页
作者
J Mous; H Stunnenberg; O Georgiev; M L Birnstiel;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类细胞生物学;
关键词

相似文献

外文文献
中文文献
专利

1. Expression of the psbDII gene in Synechococcus sp. strain PCC 7942 requires sequences downstream of the transcription start site. [J] . S A Bustos, S S Golden Journal of bacteriology . 1991,第23期

机译：psbDII基因在Synechococcus sp。中的表达。 PCC 7942菌株需要转录起始位点下游的序列。
2. Tripartite sequences within and 3' to the sea urchin H2A histone gene display properties associated with a transcriptional termination process. [J] . M R Johnson, C Norman, M A Reeve, Molecular and Cellular Biology . 1986,第11期

机译：海胆H2A组蛋白基因内部和3'端的三方序列显示与转录终止过程相关的特性。
3. The synthesis of authentic sea urchin transcriptional and translational products by sea urchin histone genes injected into Xenopus laevis oocytes☆ [J] . Laurence D. Etkin, Robert E. Maxson Jr. Developmental biology . 1980,第1期

机译：注入非洲爪蟾卵母细胞的海胆组蛋白基因合成正宗的海胆转录和翻译产物☆
4. A PARAMETRIC JOINT MODEL OF DNA-PROTEIN BINDING, GENE EXPRESSION AND DNA SEQUENCE DATA TO DETECT TARGET GENES OF A TRANSCRIPTION FACTOR [C] . WEI PAN, PENG WEI, ARKADY KHODURSKY Pacific Symposium on Biocomputing; 20080104-08; Kohala Coast,HI(US) . 2008

机译：DNA-蛋白质结合，基因表达和DNA序列数据的参数联合模型检测转录因子的靶基因
5. Regulation of gene transcription by the histone H2A and H2B N -terminal domains [D] . Parra, Michael Anthony 2007

机译：通过组蛋白H2A和H2B N末端域对基因转录的调控
6. Stimulation of sea urchin H2B histone gene transcription by a chromatin-associated protein fraction depends on gene sequences downstream of the transcription start site. [O] . J Mous, H Stunnenberg, O Georgiev, 1985

机译：染色质相关蛋白部分刺激海胆H2B组蛋白基因转录取决于转录起始位点下游的基因序列。
7. Stimulation of sea urchin H2B histone gene transcription by a chromatin-associated protein fraction depends on gene sequences downstream of the transcription start site. [O] . Mous, J, Stunnenberg, H, Georgiev, O, 1985

机译：染色质相关蛋白部分刺激海胆H2B组蛋白基因转录取决于转录起始位点下游的基因序列。

Stimulation of sea urchin H2B histone gene transcription by a chromatin-associated protein fraction depends on gene sequences downstream of the transcription start site.

摘要

著录项

相似文献

相关主题

期刊订阅