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首页> 外文期刊>Molecular and Cellular Biology >A burst of c-fos gene expression in the mouse occurs at birth.
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A burst of c-fos gene expression in the mouse occurs at birth.

机译：小鼠出生时会出现c-fos基因表达的爆发。

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摘要

Expression of the c-fos gene during murine perinatal development was studied. Before birth, all eight of the prenatal organs tested expressed undetectable or low levels of c-fos mRNA. On the day of birth, there occurred a 10- to 100-fold increase in the level of c-fos message in all of these organs. The expression was transient, in that 1 day after birth, the level of c-fos mRNA precipitously dropped. The c-fos gene expression at birth is unrelated to the expression of the c-myc gene and major histocompatibility complex class I genes, which display distinct kinetics during the perinatal development. The c-fos gene was also expressed locally and transiently in the gravid uterus 1 to 2 days prior to delivery. These results indicate that an event associated with birth induced c-fos gene expression in the mother and newborn.
机译：研究了小鼠围生期发育过程中c-fos基因的表达。出生前，测试的所有八个产前器官均表达出无法检测或水平较低的c-fos mRNA。在出生的那天，所有这些器官中的c-fos信息水平增加了10到100倍。表达是短暂的，在出生后的第一天，c-fos mRNA的水平急剧下降。出生时的c-fos基因表达与c-myc基因和主要的组织相容性复合体I类基因的表达无关，它们在围产期发育过程中表现出不同的动力学。在分娩前1-2天，c-fos基因也在妊娠子宫中局部和瞬时表达。这些结果表明，与出生有关的事件在母亲和新生儿中诱导了c-fos基因表达。

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