Dual functions of a cis-acting element within the rat prolactin gene promoter.

E A Barron; Z Cao; B G Schneider; E Kraig; A J Carrillo; Z D Sharp

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Dual functions of a cis-acting element within the rat prolactin gene promoter.

机译：大鼠催乳激素基因启动子中顺式作用元件的双重功能。

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Within the promoter region of the rat prolactin gene lies a TA-rich imperfect palindrome. The possible functions of the 18-base-pair symmetrical sequence were investigated by using an in vitro transcription system. Prolactin templates with and without the palindrome were transcriptionally assayed in both pituitary and nonpituitary extracts. Our results indicated that the palindromic sequence has at least two functions in the regulation of prolactin transcription.

机译：在大鼠催乳激素基因的启动子区域内有一个富含TA的不完善回文。通过使用体外转录系统研究了18个碱基对对称序列的可能功能。在垂体和非垂体提取物中均对含和不含回文的催乳素模板进行了转录分析。我们的结果表明回文序列在催乳素转录的调节中至少具有两个功能。

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《Molecular and Cellular Biology》 |1989年第2期|共3页
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E A Barron; Z Cao; B G Schneider; E Kraig; A J Carrillo; Z D Sharp;
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中图分类细胞生物学;
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Dual functions of a cis-acting element within the rat prolactin gene promoter.

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