Transcription activates RecA-promoted homologous pairing of nucleosomal DNA.

H Kotani; E B Kmiec

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Transcription activates RecA-promoted homologous pairing of nucleosomal DNA.

机译：转录激活RecA促进的核小体DNA同源配对。

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RecA protein catalyzes the homologous pairing of a single-stranded circular DNA and a linear duplex DNA molecule. When the duplex is packaged into chromatin, formation of homologously paired complexes is blocked. We have established a system for studying the RecA-promoted reaction by using a duplex fragment containing a single-phased nucleosome. Under these conditions there is no reaction leading to formation of joint molecule complexes. However, transcription on the chromatin template activates the formation of complexes. Reaction is dependent on RNA synthesis and DNA sequence homology and proceeds regardless of the direction of transcription.

机译：RecA蛋白催化单链环状DNA和线性双链DNA分子的同源配对。当双链体包装成染色质时，同源配对复合物的形成被阻止。我们已经建立了一个系统，通过使用包含单相核小体的双链体片段来研究RecA促进的反应。在这些条件下，没有反应导致接头分子复合物的形成。但是，染色质模板上的转录激活复合物的形成。反应取决于RNA合成和DNA序列的同源性，并且无论转录方向如何，反应都会进行。

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《Molecular and Cellular Biology》 |1994年第3期|共7页
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H Kotani; E B Kmiec;
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中图分类细胞生物学;
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1. Single-Molecular AFM Probing of Specific DNA Sequencing Using RecA-Promoted Homologous Pairing and Strand Exchange [J] . Gi Hun Seong, Tomohisa Niimi, Yasuko Yanagida Analytical chemistry . 2000,第6期

机译：使用RecA促进的同源配对和链交换的单分子AFM探测特定的DNA序列
2. A lattice model for transcription factor access to nucleosomal DNA. [J] . Teif VB, Ettig R, Rippe K Biophysical Journal . 2010,第8期

机译：转录因子访问核小体DNA的晶格模型。
3. The methyl-CpG binding transcriptional repressor MeCP2 stably associates with nucleosomal DNA. [J] . Chandler SP, Guschin D, Landsberger N, Biochemistry . 1999,第22期

机译：甲基-CPG结合转录抑制剂MECP2稳定地与核体DNA相关联。
4. An Investigation of Homologous and Non-homologous Somatic Pairing by Interchromosomal Chromatin Connectives in Citrus ichangensis [C] . G. L. Liang, S. Q. Xiang, W. X. Wang, International citrus congress . 2010

机译：在柑橘伊氏植物中的同胞形元染色质结合的同源和非同源体细胞配对的研究
5. Two Methods of Analyse DNA Sequences: Predicting Coding Regions and Clustering Homologous DNA. [D] . Zhao, Bo. 2011

机译：分析DNA序列的两种方法：预测编码区域和聚类同源DNA。
6. Transcription activates RecA-promoted homologous pairing of nucleosomal DNA. [O] . H Kotani, E B Kmiec 1994

机译：转录激活RecA促进的核小体DNA同源配对。
7. Transcription activates RecA-promoted homologous pairing of nucleosomal DNA. [O] . Kotani, H, Kmiec, E B 1994

机译：转录激活RecA促进的核小体DNA同源配对。
8. Characterization of Acinetobacter calcoaceticus catM, a Repressor Gene Homologous in Sequence to Transcriptional Activator Genes. [R] . Neidle, E. L., Hartnett, C., Ornston, L. N. 1989

机译：表征醋酸钙不动杆菌catm，一种与转录激活因子基因序列同源的阻遏基因。

Transcription activates RecA-promoted homologous pairing of nucleosomal DNA.

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