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首页> 外文期刊>Molecules >Wound-Healing Peptides for Treatment of Chronic Diabetic Foot Ulcers and Other Infected Skin Injuries
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Wound-Healing Peptides for Treatment of Chronic Diabetic Foot Ulcers and Other Infected Skin Injuries

机译：伤口愈合肽，用于治疗慢性糖尿病足溃疡和其他感染的皮肤损伤

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As the incidence of diabetes continues to increase in the western world, the prevalence of chronic wounds related to this condition continues to be a major focus of wound care research. Additionally, over 50% of chronic wounds exhibit signs and symptoms that are consistent with localized bacterial biofilms underlying severe infections that contribute to tissue destruction, delayed wound-healing and other serious complications. Most current biomedical approaches for advanced wound care aim at providing antimicrobial protection to the open wound together with a matrix scaffold (often collagen-based) to boost reestablishment of the skin tissue. Therefore, the present review is focused on the efforts that have been made over the past years to find peptides possessing wound-healing properties, towards the development of new and effective wound care treatments for diabetic foot ulcers and other skin and soft tissue infections. View Full-Text
机译：随着西方世界中糖尿病的发病率持续增加，与这种情况相关的慢性伤口的流行仍然是伤口护理研究的主要重点。此外，超过50％的慢性伤口显示出与严重细菌感染下的局部细菌生物膜一致的体征和症状，这些细菌生物膜导致组织破坏，伤口愈合延迟和其他严重并发症。当前用于高级伤口护理的大多数生物医学方法旨在与基质支架（通常基于胶原蛋白）一起为开放伤口提供抗菌保护，以促进皮肤组织的重建。因此，本综述着眼于过去几年中为发现具有伤口愈合特性的肽而进行的努力，以开发新的有效的糖尿病足溃疡以及其他皮肤和软组织感染的伤口护理疗法。查看全文

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