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Specific identification of human transferrin conformations using a cyanine dye supramolecular assembly

机译:使用花青染料超分子组装物特异性鉴定人转铁蛋白构象

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A new method to recognize human transferrin (Tf) conformations was developed using a cyanine dye supramolecular assembly. We achieved detection of the open conformation of Tf (apo-Tf) in a sub-micromolar level against the closed one (holo-Tf). As a protein conformational probe, it's promising to monitor the transition between the two conformations of Tf.
机译:开发了一种新的方法来识别人类转铁蛋白(Tf)构象,使用花青染料超分子组装。我们实现了以亚微摩尔水平相对于封闭分子(holo-Tf)检测Tf(apo-Tf)的开放构象。作为蛋白质构象探针,有望监测Tf两种构象之间的过渡。

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