Specific identification of human transferrin conformations using a cyanine dye supramolecular assembly

Zhang Xiufeng; Lan Ling; Yang Shu; Rui Yulan; Li Qian; Chen Hongbo; Sun Xin; Yang Qianfan; Tang Yalin

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Specific identification of human transferrin conformations using a cyanine dye supramolecular assembly

机译：使用青色染料超分子组装的人转铁蛋白构象的具体鉴定

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A new method to recognize human transferrin (Tf) conformations was developed using a cyanine dye supramolecular assembly. We achieved detection of the open conformation of Tf ( apo-Tf) in a sub-micromolar level against the closed one (holo-Tf). As a protein conformational probe, it's promising to monitor the transition between the two conformations of Tf.

机译：使用青色染料超分子组件开发了一种识别人转化素（TF）构象的新方法。我们在副微摩拉水平上达到了对闭孔（HOLO-TF）的亚微型摩尔水平的开放构象的检测到检测到检测TF（APO-TF）。作为蛋白质构象探针，有希望监测TF的两个构象之间的过渡。

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《RSC Advances》 |2017年第71期|共4页
作者
Zhang Xiufeng; Lan Ling; Yang Shu; Rui Yulan; Li Qian; Chen Hongbo; Sun Xin; Yang Qianfan; Tang Yalin;
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作者单位

North China Univ Sci &

Technol Coll Chem Engn Tangshan 063210 Peoples R China;

North China Univ Sci &

Technol Coll Chem Engn Tangshan 063210 Peoples R China;

Sichuan Univ West China Sch Pharm Chengdu 610064 Sichuan Peoples R China;

North China Univ Sci &

Technol Coll Chem Engn Tangshan 063210 Peoples R China;

Chinese Acad Sci Beijing Natl Lab Mol Sci Inst Chem State Key Lab Struct Chem Unstable &

Stable Speci Beijing 100190 Peoples R China;

Grad Univ Chinese Acad Sci Beijing 100080 Peoples R China;

North China Univ Sci &

Technol Coll Chem Engn Tangshan 063210 Peoples R China;

Sichuan Univ Coll Chem Chengdu 610065 Sichuan Peoples R China;

Chinese Acad Sci Beijing Natl Lab Mol Sci Inst Chem State Key Lab Struct Chem Unstable &

Stable Speci Beijing 100190 Peoples R China;

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正文语种 eng
中图分类化学;
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1. Specific identification of human transferrin conformations using a cyanine dye supramolecular assembly [J] . Zhang Xiufeng, Lan Ling, Yang Shu, RSC Advances . 2017,第71期

机译：使用青色染料超分子组装的人转铁蛋白构象的具体鉴定
2. Verification Of Specific G-quadruplex Structure By Using A Novel Cyanine Dye Supramolecular Assembly: I. Recognizing Mixed G-quadruplex In Human Telomeres [J] . Qianfan Yang, Junfeng Xiang, Shu Yang, Chemical Communications . 2009,第9期

机译：通过使用新型花菁染料超分子组装的特定G四联体结构的验证：I.识别人类端粒中的混合G四联体。
3. Visualized detection of apo-transferrin based on cyanine dye supramolecular assembly [J] . Lang Yunhe, Shi Lei, Lan Ling, Spectrochimica acta, Part A. Molecular and biomolecular spectroscopy . 2019,第期

机译：基于青色染料超分子组装的APO-转铁蛋白的可视化检测
4. Title: Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: Ⅱ. The binding characterization with specific intramolecular G-quadruplex and the recognizing mechanism [C] . Qianfan Yang, Guangzhi Xu, Junfeng Xiang, ICMSI;International conference of molecular simulations and applied informatics technologies . 2010

机译：标题：通过使用新型花青染料超分子组装验证特定的G-四链体结构：Ⅱ。特定分子内G-四链体的结合表征及识别机理
5. DNA templated supramolecular assemblies of cyanine dyes [D] . Benvin, Andrea L. 2008

机译：DNA模板的花菁染料的超分子组装
6. Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: II. The binding characterization with specific intramolecular G-quadruplex and the recognizing mechanism [O] . Qianfan Yang, Junfeng Xiang, Shu Yang, 2010

机译：通过使用新型花菁染料超分子组装验证特定的G-四链体结构：II.。特定分子内G-四链体的结合表征及识别机理
7. Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: II. The binding characterization with specific intramolecular G-quadruplex and the recognizing mechanism [O] . Yang, Qianfan, Xiang, Junfeng, Yang, Shu, 2009

机译：通过使用新型花菁染料超分子组装验证特定的G-四链体结构：II.。特定分子内G-四链体的结合表征及识别机理

Specific identification of human transferrin conformations using a cyanine dye supramolecular assembly

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