• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Self-healable hydrogels with NaHCO3 degradability and a reversible gel–sol–gel transition from phenolic ester containing polymers
【24h】

Self-healable hydrogels with NaHCO3 degradability and a reversible gel–sol–gel transition from phenolic ester containing polymers

机译：具有NaHCO 3 的可降解性的自修复水凝胶，并且由含酚酯的聚合物实现可逆的凝胶-溶胶-凝胶转变

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Due to their fantastic self-healing property, similar to that of organisms, self-healable hydrogels have attracted considerable attention in recent years. Herein, self-healable hydrogels with degradability in NaHCO3 were prepared and showed a reversible gel–sol–gel transition under a variety triggers. The hydrogel was prepared from poly(N,N-dimethylacrylamide-stat-4-formylphenyl acrylate), P(DMA-stat-FPA), and dihydrazide with dynamic acylhydrazone and disulfide cross-linking. With base labile phenolic ester bond connections, the hydrogel can be degraded by the extremely mild base, NaHCO3 solution. With a dihydrazide compound as a cross-linker, the hydrogel formed and self-healed without any additional catalysis or stimulus. Moreover, the self-healable hydrogels showed a reversible gel–sol–gel transition under various conditions, including pH, redox and group ratios, based on the reversible characteristics of acylhydrazone and disulfide bonds. With these superior properties, the developed hydrogel holds great potential for applications in many biomedical fields, including tissue engineering, drug delivery carriers and biosensors.
机译：由于其与生物类似的出色的自我修复特性，近年来，可自我修复的水凝胶备受关注。在此，制备了在NaHCO 3 中具有可降解性的自修复水凝胶，并在多种触发条件下显示出可逆的凝胶-溶胶-凝胶转变。该水凝胶由聚（em）N ， N -二甲基丙烯酰胺- stat -4-甲酰基丙烯酸苯酯），P（DMA- stat -FPA），并与二酰肼与动态酰基hydr和二硫键交联。通过碱不稳定的酚酯键连接，水凝胶可被极其温和的碱NaHCO 3 溶液降解。用二酰肼化合物作为交联剂，水凝胶形成并自我修复，而没有任何其他催化或刺激。此外，基于酰基hydr和二硫键的可逆特性，可自修复的水凝胶在各种条件下（包括pH，氧化还原和基团比）显示出可逆的凝胶-溶胶-凝胶转变。凭借这些优越的性能，开发的水凝胶在许多生物医学领域具有广阔的应用潜力，包括组织工程，药物输送载体和生物传感器。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号