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Technological advances in current metabolomics and its application in tradition Chinese medicine

机译：当前代谢组学的技术进步及其在中医药中的应用

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During the last few years, many metabolomics technologies have been established in biomedical research for analyzing the changes of metabolite levels. They have also become important tools in the field of life sciences and are widely applied to discover innovative drugs, providing valuable methods to explore the function and essence of formulas in traditional Chinese medicine (TCM) research. Metabolomics shows major potential to provide a unique perspective for disease diagnosis and elucidate the action mechanism of TCM by measuring endogenous metabolites in biofluids. With the gradual expansion of the application fields of metabolomics, the related number of techniques is increasing day by day. The techniques of choice for the study of various low-molecular-weight metabolic pathways, and for the analysis of metabolites in search of the changes of biomarkers in TCM treatment of disease in biological samples include nuclear magnetic resonance (NMR) spectroscopy, chromatography coupled with mass spectrometry, and so forth. These techniques have been proven to be powerful tools for the detection of metabolites and biomarkers. Here, we will introduce the newly used analytical techniques for metabolomics, and metabolomics in TCM is also summarized.
机译：在过去的几年中，生物医学研究中已经建立了许多代谢组学技术来分析代谢物水平的变化。它们也已成为生命科学领域的重要工具，并广泛用于发现创新药物，为探索中药研究中配方的功能和本质提供了有价值的方法。代谢组学显示出巨大的潜力，可通过测量生物流体中的内源性代谢产物，为疾病诊断提供独特的视角并阐明中药的作用机制。随着代谢组学的应用领域的逐渐扩大，相关技术的数量正日益增加。研究各种低分子量代谢途径和分析代谢物以寻找中药治疗生物样品中疾病的生物标志物变化的选择技术包括核磁共振（NMR）光谱，与质谱分析等等。这些技术已被证明是检测代谢物和生物标志物的有力工具。在这里，我们将介绍新近使用的代谢组学分析技术，并对中医中的代谢组学进行总结。

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