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首页> 外文期刊>RSC Advances >Novel alkyl chain-based fluorescent probes with large Stokes shifts used for imaging the cell membrane and mitochondria in different living cell lines
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Novel alkyl chain-based fluorescent probes with large Stokes shifts used for imaging the cell membrane and mitochondria in different living cell lines

机译：具有大斯托克斯位移的新型基于烷基链的荧光探针，用于对不同活细胞系中的细胞膜和线粒体进行成像

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Fluorescent dyes with large Stokes shifts play a key role in developing multi-purpose fluorescent probes for a wide variety of targets. In this study, we developed two novel alkyl chain-based fluorescent probes (CA-C12 and CA-C2) with large Stokes shifts. The alkyl chain length of the probes affect the membrane permeability, and hence both probes can be successfully applied for sensing the cell membrane and mitochondria in different living cell lines. Furthermore, the probes CA-C12 and CA-C2 exhibited large Stokes shifts and excellent photostability in the different cell lines. The fluorescent dyes with large Stokes shifts were expected to have broader applications for developing various fluorescent probes with excellent optical properties.
机译：具有大斯托克斯位移的荧光染料在开发用于多种靶标的多功能荧光探针中起着关键作用。在这项研究中，我们开发了两种新颖的具有大斯托克斯位移的基于烷基链的荧光探针（CA-C12和CA-C2）。探针的烷基链长度会影响膜的通透性，因此两种探针均可成功用于检测不同活细胞系中的细胞膜和线粒体。此外，探针CA-C12和CA-C2在不同细胞系中表现出大的斯托克斯位移和优异的光稳定性。期望具有大斯托克斯位移的荧光染料在开发具有优异光学性能的各种荧光探针方面具有更广泛的应用。

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