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Dioxygen insensitive C70/AuNPs hybrid system for rapid and quantitative glucose biosensing

机译:双氧不敏感的C 70 / AuNPs杂交系统用于快速定量葡萄糖生物传感

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A novel hybrid system based on NAD-dependent glucose dehydrogenase immobilized on gold nanoparticles (AuNPs) covered with C70 fullerene has been developed for effective biosensing and quantitative detection of glucose. According to amperometric measurements, the new biosensor exhibited high sensitivity (26.1 μA mM?1 cm?2), wide linear range (0.25–12.0 mM), and rapid characteristic response (3 s). These unique properties suggest that the prepared hybrid nanocomposite is very promising to find potential application as a dioxygen insensitive biosensor for rapid and quantitative detection of glucose.
机译:为了有效地对葡萄糖进行生物传感和定量检测,开发了一种基于NAD依赖性葡萄糖脱氢酶的新型杂化体系,该体系固定在C 70 富勒烯覆盖的金纳米颗粒(AuNPs)上。根据安培测量,新型生物传感器显示出高灵敏度(26.1μAmM ?1 cm ?2 ),线性范围广(0.25-12.0 mM),特征响应快(3 s)。这些独特的性质表明,制备的杂化纳米复合材料非常有前景,有望作为对双氧不敏感的生物传感器用于葡萄糖的快速定量检测。

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