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Quantum Dot / Optical Protein Bio-Nano Hybrid System for Biosensing Applications

机译:用于生物传感应用的量子点/光学蛋白生物纳米混合系统

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The unique energy transfer interaction between the optical protein bacteriorhodopsin (bR) and CdSe/ZnS quantum dots (QDs) provides a potential modulation mechanism for bio-nano electronic application. We have utilized ionic-self assembled monolayer (I-SAM) techniques to create a novel alternating monolayer system of QDs and bR on a conductive ITO substrate. Results demonstrate the ability to efficiently create bR/QD multilayer films along with the ability to control bR/QD spacing on the nanometer scale. I-SAM films of this nature demonstrate a sharp decrease in QD emission when deposited in close proximity to bR, suggesting possible fluorescence resonance energy transfer (FRET) effects in a bR/QD nanoscale system. The ability to modulate the QD photonic output based on proximity to bR in the ISAM films could provide a direct method to modulate the electrical output for bio-nano sensing applications.

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