• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >A novel near-infrared fluorescent probe for highly selective recognition of hydrogen sulfide and imaging in living cells
【24h】

A novel near-infrared fluorescent probe for highly selective recognition of hydrogen sulfide and imaging in living cells

机译：一种新型的近红外荧光探针，可高度选择性地识别硫化氢并在活细胞中成像

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A novel near-infrared fluorescent probe ( L ) based on a 1,4-diethyl-1,2,3,4-tetrahydro-7 H -pyrano[2,3- g ]quinoxalin-7-one scaffold has been synthesized and characterized. Probe L displays highly selective and sensitive recognition to H _(2) S over various anions and biological thiols with a large Stokes shift (125 nm) in THF/H _(2) O (6/4, v/v, Tris–HCl 10 mM, pH = 7.4). This probe exhibits turn-on fluorescence for H _(2) S through HS ~(?) induced thiolysis of dinitrophenyl ether. Confocal laser scanning micrographs of MCF-7 cells incubated with L confirm that L is cell-permeable and can successfully detect H _(2) S in living cells.
机译：合成了一种新型的基于1,4-二乙基-1,2,3,4-四氢-7 H-吡喃并[2,3-g]喹喔啉-7-one支架的近红外荧光探针，表征。探针L在THF / H _（2）O（6/4，v / v，Tris–中）对各种阴离子和具有较大斯托克斯位移（125 nm）的生物硫醇表现出对H _（2）S的高度选择性和敏感性。 HCl 10 mM，pH = 7.4）。该探针通过HS〜（？）诱导的二硝基苯醚的硫解，显示出H_（2）S的开启荧光。用L培养的MCF-7细胞的共聚焦激光扫描显微照片证实L是可渗透细胞的，并且可以成功检测活细胞中的H _（2）S。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号