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首页> 外文期刊>RSC Advances >Biomaterials from human bone – probing organic fraction removal by chemical and enzymatic methods
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Biomaterials from human bone – probing organic fraction removal by chemical and enzymatic methods

机译：人体骨骼中的生物材料-通过化学和酶促方法探测有机物去除

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Two different deproteination and defatting processes of human bone were investigated, by combined infrared and neutron techniques: a previously reported hydrazine extraction and a newly developed multi-enzymatic treatment. Complementary Fourier transform infrared total attenuated reflectance and inelastic neutron scattering spectroscopies were applied, allowing access to all vibrational modes of the samples. The effectiveness of the different experimental protocols for removing the organic constituents of bone (lipids and protein) was probed, as well as their effect on bone's structural and crystallinity features. The results thus gathered are expected to have an impact on bioanthropological, archaeological and medical sciences, namely regarding the development of novel biocompatible materials for orthopaedic xenografts.
机译：通过结合红外和中子技术研究了人类骨骼的两种不同的脱蛋白和脱脂过程：先前报道的肼提取和新开发的多酶处理方法。使用了互补傅里叶变换红外全衰减反射率和非弹性中子散射光谱学，可以访问样品的所有振动模式。探讨了不同实验方案去除骨骼有机成分（脂质和蛋白质）的有效性，以及它们对骨骼的结构和结晶度特征的影响。预期由此收集的结果将对生物人类学，考古学和医学科学产生影响，即在开发用于骨科异种移植物的新型生物相容性材料方面。

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