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White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation

机译:共轭聚电解质通过单线态氧产生白光诱导的细胞凋亡

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摘要

A cationic conjugated polyelectrolyte (CPE) PPET3 with a poly( p -phenylene ethynylene terthiophene) backbone and quaternary ammonium side chains was designed and synthesized. It serves as an efficient photosensitizer for photodynamic therapy under white light irradiation and induces cell death through the mitochondrial apoptosis pathway.
机译:设计并合成了具有聚对苯撑乙炔亚乙基对噻吩骨架和季铵侧链的阳离子共轭聚电解质(CPE)PPET3。它是在白光照射下进行光动力治疗的有效光敏剂,并通过线粒体凋亡途径诱导细胞死亡。

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