White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation

Liang Jiamei; Wu Pan; Tan Chunyan; Jiang Yuyang

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White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation

机译：通过单次氧气产生共轭聚电解质白光诱导的细胞凋亡

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A cationic conjugated polyelectrolyte (CPE) PPET3 with a poly(p-phenylene ethynylene terthiophene) backbone and quaternary ammonium side chains was designed and synthesized. It serves as an efficient photosensitizer for photodynamic therapy under white Eight irradiation and induces cell death through the mitochondrial apoptosis pathway.

机译：设计并合成了具有聚（对亚苯基乙炔基苯甲酸苯甲烯）主链和季铵侧链的阳离子共轭聚电解质（CPE）PPET3。它用作白八辐射下的光动力治疗的有效光敏剂，通过线粒体凋亡途径诱导细胞死亡。

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《RSC Advances》 |2018年第17期|共5页
作者
Liang Jiamei; Wu Pan; Tan Chunyan; Jiang Yuyang;
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作者单位

Tsinghua Univ Dept Chem Beijing 100084 Peoples R China;

Tsinghua Univ Dept Chem Beijing 100084 Peoples R China;

Tsinghua Univ Dept Chem Beijing 100084 Peoples R China;

Tsinghua Univ Grad Sch Shenzhen State Key Lab Chem Oncogen Shenzhen 518055 Peoples R China;

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正文语种 eng
中图分类化学;
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1. White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation [J] . Liang Jiamei, Wu Pan, Tan Chunyan, RSC Advances . 2018,第17期

机译：通过单次氧气产生共轭聚电解质白光诱导的细胞凋亡
2. Singlet oxygen treatment of tumor cells triggers extracellular singlet oxygen generation, catalase inactivation and reactivation of intercellular apoptosis-inducing signaling [J] . Michaela Riethmüller, Nils Burger, Georg Bauer Redox Biology . 2015,第1期

机译：肿瘤细胞的单线态氧治疗会触发细胞外单线态氧的产生，过氧化氢酶的失活以及细胞间凋亡诱导信号的重新激活
3. Light-Induced Generation of Singlet Oxygen by Naked Gold Nanoparticles and its Implications to Cancer Cell Phototherapy [J] . George Pasparakis Small . 2013,第24期

机译：裸金纳米粒子光诱导单线态氧的产生及其对癌细胞光疗的意义
4. Kinetic analysis of singlet oxygen generation in a living cell using Singlet Oxygen Sensor Green [C] . Yi Shen, Huiyun Lin, Zufang Huang, Optics in health care and biomedical optics IV . 2010

机译：使用单重态氧传感器Green进行活细胞中单重态氧生成的动力学分析
5. MECHANISMS OF PHOTOOXIDATIONS: ELECTRON-TRANSFER TO SINGLET OXYGEN, SUBSTRATE ENHANCED INTERSYSTEM CROSSING AS A SOURCE OF SINGLET OXYGEN AND SINGLET OXYGEN-OLEFIN INTERACTIONS. [D] . MANRING, LEWIS EDWARD. 1982

机译：光氧化的机理：电子转移到单氧，基质增强的系统间交叉作为单氧的来源和单氧-烯烃相互作用。
6. Singlet oxygen treatment of tumor cells triggers extracellular singlet oxygen generation catalase inactivation and reactivation of intercellular apoptosis-inducing signaling [O] . Michaela Riethmüller, Nils Burger, Georg Bauer 2015

机译：肿瘤细胞的单线态氧治疗可触发细胞外单线态氧的产生过氧化氢酶的失活以及细胞间凋亡诱导信号的重新活化
7. Singlet oxygen treatment of tumor cells triggers extracellular singlet oxygen generation, catalase inactivation and reactivation of intercellular apoptosis-inducing signaling [O] . Riethmüller Michaela, Burger Nils, Bauer Georg 2015

机译：肿瘤细胞的单线态氧治疗可触发细胞外单线态氧的产生，过氧化氢酶的失活以及细胞间凋亡诱导信号的重新激活

White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation

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