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Bioscaffold arrays decorated with Ag nanoparticles as a SERS substrate for direct detection of melamine in infant formula

机译:以Ag纳米颗粒为SERS底物的生物支架阵列可直接检测婴儿配方食品中的三聚氰胺

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Three-dimensional (3D) plasmonic structures have been intensively investigated as high performance surface enhanced Raman scattering (SERS) substrates. Here, we demonstrate a 3D biomimetic SERS substrate prepared by deposition of silver nanoparticles (Ag NPs) on the bioscaffold arrays of cicada wings using laser molecular beam epitaxy. This deposition method can offer a large number of nanoparticles with average diameter of ~10 nm and nanogaps of sub-10 nm on the surface of chitin nanopillars to generate a high density of hotspots. The prepared 3D Ag/cicada SERS substrate shows a limit of detection (LOD) for Rhodamine 6G as low as 10 ~(?7) M, high enhancement factor of 1.09 × 10 ~(5) , and excellent signal uniformity of 6.8%. Moreover, the molecular fingerprints of melamine in infant formula can be directly extracted with an LOD as low as 10 mg L ~(?1) , without the need for functional modification. The prepared SERS-active substrate, due to its low cost, high-throughput, and good detection performance, can be widely used in applications such as food safety and environmental monitoring.
机译:三维(3D)等离子体激元结构已作为高性能表面增强拉曼散射(SERS)衬底进行了深入研究。在这里,我们演示了一种3D仿生SERS衬底,该衬底是通过使用激光分子束外延将银纳米颗粒(Ag NP)沉积在蝉翼的生物支架阵列上而制备的。这种沉积方法可以在几丁质纳米柱的表面上提供大量平均直径约为10 nm的纳米颗粒和低于10 nm的纳米间隙,从而产生高密度的热点。制备的3D Ag /蝉SERS底物对罗丹明6G的检出限(LOD)低至10〜(?7)M,1.09×10〜(5)的高增强因子和6.8%的出色信号均匀性。而且,婴儿配方食品中三聚氰胺的分子指纹可以用低至10 mg L〜(?1)的LOD直接提取,而无需进行功能修饰。所制备的SERS活性底物由于其低成本,高通量和良好的检测性能,可广泛用于食品安全和环境监测等应用中。

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