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首页> 外文期刊>Journal of Clinical Microbiology >Nosocomial colonization and infection by Achromobacter xylosoxidans.
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Nosocomial colonization and infection by Achromobacter xylosoxidans.

机译：木聚糖氧化无色杆菌在医院内定植和感染。

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Achromobacter xylosoxidans, a bacterial species named in 1971, is often isolated from aqueous environments, but little has been reported about its pathogenicity in humans, its epidemiological pattern, and its susceptibility to antibiotics and antiseptics. We were faced with an epidemic caused by this microorganism for 18 months in an intensive care unit. Two patients had fatal infections and 37 others were colonized. The source was the deionized water of the hemodialysis system. The 46 isolates were identified by comparison with the reference strain A. xylosoxidans ATCC 27061. The characteristic cellular fatty acids of this species were demonstrated by gas-liquid chromatography. The minimal inhibitory concentrations of 27 antibiotics were determined. The isolates were susceptible to only two: moxalactam at 4 micrograms/ml and ceftazidime at 8 micrograms/ml. The minimal bactericidal concentrations of one disinfectant and three antiseptics were: sodium hypochloride, 109 micrograms/ml; chlorhexidine digluconate in ethanol solution, 15 to 125 micrograms/ml; polyvinylpyrrolidone iodine, 750 micrograms/ml; and iodine ethanol, 312 to 625 micrograms/ml.
机译：木氧化无色杆菌，一种1971年命名的细菌，通常从水环境中分离出来，但是关于其对人的致病性，流行病学模式以及对抗生素和防腐剂的敏感性的报道很少。在重症监护室中，我们因这种微生物引起的流行病持续了18个月。两名患者致命感染，另外37例定植。来源是血液透析系统的去离子水。通过与参考菌株A. xylosoxidans ATCC 27061进行比较，鉴定出46种分离物。通过气液色谱法证明了该菌种的特征性细胞脂肪酸。确定了27种抗生素的最低抑菌浓度。分离株仅对两种敏感：莫沙内酰胺4微克/毫升和头孢他啶8微克/毫升。一种消毒剂和三种消毒剂的最低杀菌浓度为：次氯酸钠109微克/毫升;在乙醇溶液中的葡萄糖酸氯己定二葡萄糖，15至125微克/毫升;聚乙烯吡咯烷酮碘，750微克/毫升;和碘乙醇，浓度为312至625微克/毫升。

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