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首页> 外文期刊>Journal of Clinical Microbiology >Evaluation of cellular substrates for antinuclear antibody determinations.
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Evaluation of cellular substrates for antinuclear antibody determinations.

机译:评估细胞底物的抗核抗体测定。

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The immunofluorescent technique was employed to evaluate the sensitivity of 10 human and animal cell monolayers and tissue sections as substrates for titering the antinuclear antibody content of serum samples. The highest mean ranks of sensitivity, the relative ability of each substrate to maintain its sensitivity rank when 21 selected positive sera were tested, were achieved by two fibroblast cell lines, baby hamster kidney (BHK 21/C13) and human lung (WI-38), respectively. The least sensitive substrates were commercial rat kidney and liver tissue sections.
机译:免疫荧光技术用于评估10个人和动物细胞单层和组织切片作为滴定血清样品中抗核抗体含量的底物的敏感性。通过两种成纤维细胞系,仓鼠肾(BHK 21 / C13)和人肺(WI-38)获得最高的平均敏感性等级,即每种底物在检测21种选定的阳性血清时维持其敏感性等级的相对能力。 ), 分别。最不敏感的底物是商业大鼠的肾脏和肝脏组织切片。

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