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首页> 外文期刊>Journal of Clinical Microbiology >Latex agglutination tests for measurement of antiplague antibodies.
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Latex agglutination tests for measurement of antiplague antibodies.

机译:乳胶凝集测试,用于测量抗瘟抗体。

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A latex agglutination test was evaluated as a method for detection and titration of antiplague antibodies. Slide and microtiter techniques using polystyrene latex particles coated with specific fraction-I-antigen of Yersinia pestis were found to be comparable in specificity and sensitivity to serological tests commonly used in laboratory practice. The latex agglutination titers correlated well with those measured by the World Health Organization standard method of indirect hemagglutination, although there was a tendency for the former to be a little lower than the latter. With further study, the latex agglutination test may have application in the seroinvestigation of plague infection in rodents.
机译:乳胶凝集试验被评估为检测和滴定抗瘟抗体的方法。发现使用涂有鼠疫耶尔森氏菌特定I-抗原的聚苯乙烯乳胶颗粒的载玻片和微量滴定技术在特异性和敏感性上可与实验室实践中常用的血清学测试相媲美。乳胶凝集滴度与通过世界卫生组织间接血凝标准方法测得的滴度具有很好的相关性,尽管前者趋于略低于后者。随着进一步的研究,乳胶凝集试验可能在啮齿类动物鼠疫感染的血清学研究中得到应用。

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