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首页> 外文期刊>Journal of Clinical Microbiology >Etiology of childhood diarrhea in Korea.
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Etiology of childhood diarrhea in Korea.

机译：韩国儿童腹泻的病因学。

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To assess the role of recently recognized enteropathogens in childhood diarrhea in Korea, 231 children with diarrhea admitted to and 104 children without diarrhea seen at the well-baby clinic or the outpatient department of Hanyang University Hospital in Seoul, Korea, were evaluated during a 14-month period. Stools were cultured for bacterial pathogens, including enterotoxigenic (heat-labile and heat-stable enterotoxin-producing) and enteroadherent organisms. Only those stools obtained from patients with diarrhea were examined for rotavirus. All Escherichia coli isolates were screened for Shiga-like toxin (SLT) I, SLT-II, enterohemorrhagic E. coli fimbriae, and enteroinvasiveness by colony hybridization. One or more pathogens were identified in 75.8% of the children with diarrhea. Rotavirus was the most frequently identified pathogen, accounting for 47% of the cases. Other major enteropathogens were enterotoxigenic E. coli (22%), Clostridium difficile (16%), enteroadherent E. coli (15%), and enteropathogenic E. coli (6%). Shigella spp., Campylobacter jejuni, Salmonella spp., SLT-I-and enterohemorrhagic-E. coli-fimbria-probe-positive E. coli serotype O26:H11 and enteroinvasive E. coli were isolated from only a few patients. Aeromonas hydrophila and E. coli O157 were not isolated. Compared with those of the controls, the isolation rates of heat-stable-enterotoxin-producing E. coli (P less than 0.05), C. difficile (P less than 0.025), and enteroadherent E. coli (P less than 0.05) were significantly higher in the patients with diarrhea. The greatest number of rotavirus, enterotoxigenic E. coli, and C. difficile cases were identified during the cool, dry months of October and November.
机译：为了评估韩国最近发现的肠病原体在儿童腹泻中的作用，在韩国首尔市汉阳大学医院的门诊部或门诊部就诊的231名腹泻儿童和104名无腹泻儿童被评估为14岁儿童。月期间。培养凳子上的细菌病原体，包括产肠毒素（对热不稳定和产生热稳定性肠毒素）和肠黏附生物。仅检查从腹泻患者获得的那些粪便中的轮状病毒。通过菌落杂交对所有大肠杆菌分离物筛选志贺样毒素（SLT）I，SLT-II，肠出血性大肠杆菌菌毛和肠侵袭性。 75.8％的腹泻儿童中鉴定出一种或多种病原体。轮状病毒是最常见的病原体，占病例的47％。其他主要的肠病原体是产肠毒素的大肠杆菌（22％），艰难梭菌（16％），肠黏附性大肠杆菌（15％）和肠致病性大肠杆菌（6％）。志贺氏菌属，空肠弯曲菌，沙门氏菌属，SLT-I和肠出血性-E。仅从少数患者中分离出O26：H11大肠埃希菌-纤毛-探针阳性的大肠杆菌和肠侵袭性大肠杆菌。未分离出嗜水气单胞菌和大肠杆菌O157。与对照组相比，产生热稳定肠毒素的大肠杆菌（P小于0.05），艰难梭菌（P小于0.025）和肠黏附性大肠杆菌（P小于0.05）的分离率是腹泻患者明显更高。在10月和11月的阴凉干燥月份，发现了轮状病毒，产肠毒素的大肠杆菌和艰难梭菌病例最多。

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