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首页> 外文期刊>Journal of Clinical Microbiology >Rheumatoid factor: a cause of fals positive histoplasmin latex agglutination.
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Rheumatoid factor: a cause of fals positive histoplasmin latex agglutination.

机译:类风湿因子:组织乳胶凝集假阳性的原因。

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Ten of thirteen patients with positive histolatex agglutination titers of 1:32 or greater had no evidence of acute histoplasmosis.Three of these false positives had rheumatoid arthritis. A fourth had a rising mycoplasma complement fixation titer, and the fifth had a high titer of cold agglutinins. All of these are associated with abnormal immunoglobulin M production. To evaluate the role of rheumatoid factor in producing false positive histolatex agglutination, the histolatex test was performed on sera from 32 patients having rheumatoid factor at a titer of 1:40 or greater. Four of these sera agglutinated the histoplasmin-coated latex particles at titers of 1:32 or greater. Review of clinical records suggests the this reactivity is nonspecific. It is our purpose to call attention to rheumatoic factor as a cause of false positive histolatex agglutination.
机译:13例组织胶乳凝集滴度阳性值为1:32或更高的患者中有10例无急性组织胞浆菌病的证据。这些假阳性中有3例患有类风湿关节炎。第四位具有增加的支原体补体固定效价,第五位具有高的冷凝集素效价。所有这些都与免疫球蛋白M的异常产生有关。为了评估类风湿因子在产生假阳性组织乳胶凝集中的作用,对32名风湿因子效价为1:40或更高的患者的血清进行了组织胶乳测试。这些血清中有四个以1:32或更大的滴度凝集组织纤维蛋白包被的乳胶颗粒。临床记录的回顾表明这种反应是非特异性的。我们的目的是引起人们的注意,风湿病因子是导致假阳性组织胶凝集的原因。

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