Genomic fingerprinting of Neisseria meningitidis associated with group C meningococcal disease in Canada.

C A Strathdee; S D Tyler; J A Ryan; W M Johnson; F E Ashton

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Genomic fingerprinting of Neisseria meningitidis associated with group C meningococcal disease in Canada.

机译：加拿大脑膜炎奈瑟菌与C组脑膜炎球菌病相关的基因组指纹图谱。

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A single electrophoretic type (ET15) of Neisseria meningitidis has been associated with an increased incidence of group C meningococcal disease in Canada. Genomic fingerprinting through pulsed-field gel electrophoresis of chromosomal DNA was used to characterize the clonal relationship among meningococcal isolates of different electrophoretic types and among isolates within ET15. The genomic fingerprints of the ET15 isolates, while similar as a group, were sufficiently distinct to confirm linkage for four pairs of strains from focal outbreaks and differed markedly from those of the other common electrophoretic types, ET5, ET9, and ET21.

机译：脑膜炎奈瑟氏球菌的单一电泳类型（ET15）与加拿大C组脑膜炎球菌疾病的发病率增加有关。通过染色体DNA的脉冲场凝胶电泳进行基因组指纹分析，以表征不同电泳类型的脑膜炎球菌分离株之间以及ET15内分离株之间的克隆关系。 ET15分离株的基因组指纹虽然与一组相似，但具有足够的差异性，足以确认来自疫情爆发的四对菌株的连锁，并且与其他常见电泳类型ET5，ET9和ET21明显不同。

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《Journal of Clinical Microbiology》 |1993年第9期|共3页
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C A Strathdee; S D Tyler; J A Ryan; W M Johnson; F E Ashton;
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中图分类医学微生物学（病原细菌学、病原微生物学）;
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专利

1. An outbreak of group B meningococcal disease: tracing the causative strain of Neisseria meningitidis by DNA fingerprinting. [J] . B E Kristiansen, B S?rensen, B Bjorvatn, Journal of Clinical Microbiology . 1986,第4期

机译：B组脑膜炎球菌疾病的爆发：通过DNA指纹图谱追踪脑膜炎奈瑟菌的致病菌株。
2. An outbreak of group B meningococcal disease: tracing the causative strain of Neisseria meningitidis by DNA fingerprinting. [J] . B E Kristiansen, B S?rensen, B Bjorvatn, Journal of Clinical Microbiology . 1986,第4期

机译：B组脑膜炎球菌疾病的爆发：通过DNA指纹图谱追踪脑膜炎奈瑟菌的致病菌株。
3. Meningococcal Group B Vaccine For The Prevention Of Invasive Meningococcal Disease Caused By Neisseria meningitidis Serogroup B [J] . Irene Rivero-Calle, Peter Francis Raguindin, Jose Gómez-Rial, Infection and Drug Resistance . 2019,第3期

机译：B型脑膜炎球菌疫苗，用于预防由B型脑膜炎奈瑟菌引起的侵袭性脑膜炎球菌疾病
4. Fatal meningococcal meningitidis in a baby caused by serogroup C Neisseria meningitidis belonging to ST-4821 complex [C] . Hui Han, Haishan Li, Yu Yang, International Conference on Human Health and Medical Engineering. . 2014

机译：致命的脑膜炎球菌脑膜脑膜脑膜脑膜脑膜炎症患者由Serogroup C Neisseria Meningitidis属于ST-4821复合物
5. Characterization of the molecular epidemiology of Neisseria meningitidis and investigation of two potential risk factors associated with invasive meningococcal disease. [D] . Schmidt, Mark Andrew. 2009

机译：脑膜炎奈瑟氏菌的分子流行病学特征和与浸润性脑膜炎球菌病相关的两个潜在危险因素的研究。
6. Genomic fingerprinting of Neisseria meningitidis associated with group C meningococcal disease in Canada. [O] . C A Strathdee, S D Tyler, J A Ryan, 1993

机译：加拿大脑膜炎奈瑟菌与C组脑膜炎球菌病相关的基因组指纹图谱。
7. Genomic fingerprinting of Neisseria meningitidis associated with group C meningococcal disease in Canada [O] . C A Strathdee, S D Tyler, J A Ryan, 1993

机译：加拿大C组脑膜炎群相关脑膜炎脑膜炎的基因组指纹
8. Detection of Neisseria meningitidis Cell Envelope Antigen by Enzyme-Linked Immunosorbent Assay in Patients with Meningococcal Disease [R] . Sippel, J. E., Voller, A. 1979

机译：脑膜炎球菌病患者酶联免疫吸附法检测脑膜炎奈瑟菌细胞包膜抗原

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Genomic fingerprinting of Neisseria meningitidis associated with group C meningococcal disease in Canada.

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