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首页> 外文期刊>Journal of Clinical Microbiology >Pneumocystis carinii antigenemia in adults with malignancy, infection, or pulmonary disease.
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Pneumocystis carinii antigenemia in adults with malignancy, infection, or pulmonary disease.

机译：患有恶性肿瘤，感染或肺部疾病的成人患有卡氏肺孢子虫抗原血症。

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摘要

A counterimmunoelectrophoresis test for Pneumocystis carinii antigenemia was employed to assess the extent of subclinical infection or colonization with this agent in adults with infection, pulmonary disease, or malignancy and in healthy homosexual men. Antigenemia was detected in 6 of 208 (3%) of normal controls, 3 of 28 (11%) of patients with pulmonary infection, 3 of 33 (9%) of those with chronic lung disease, 1 of 36 (3%) of patients with lung cancer, 7 of 271 (3%) of afebrile subjects with malignancy, 6 of 19 (32%) of febrile patients with malignancy, 2 of 22 (9%) of those with nonpulmonary infection, and 0 of 21 (0%) of healthy young homosexual men. These data suggest that P. carinii is a common commensal or saprophyte that becomes clinically significant only when host defenses are impaired. Antigenemia may occur intermittently during various disease states in the absence of positive clinical signs and should alert the physician to subacute infection or colonization. Treatment appears advisable when clinical data and counterimmunoelectrophoresis results concur.
机译：使用卡那氏肺孢子虫抗原血症的抗免疫电泳测试来评估在感染，肺部疾病或恶性肿瘤的成年人以及健康的同性恋男性中亚临床感染或用这种药物定植的程度。在208名正常对照中有6名（3％），在28名肺部感染患者中有3名（11％），在慢性肺病患者中33名中有3名（9％），36名中有1名（3％）检测到了抗原血症肺癌患者，271名发热患者中的7名（3％），19名发热患者中的6名（32％），非肺部感染患者中22名中的2名（9％）和21名患者中的0名（0 ％）健康的年轻同性恋男子。这些数据表明卡氏疟原虫是常见的共生或腐生植物，仅在宿主防御能力受损时才具有临床意义。在没有阳性临床体征的情况下，各种疾病状态期间可能会间歇发生抗原血症，应提醒医生亚急性感染或定植。当临床数据和抗免疫电泳结果一致时，建议进行治疗。

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