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首页> 外文期刊>Journal of Clinical Microbiology >Susceptibility of Haemophilus influenzae to piperacillin-tazobactam combinations: interpretive criteria and quality control limits for standardized tests.
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Susceptibility of Haemophilus influenzae to piperacillin-tazobactam combinations: interpretive criteria and quality control limits for standardized tests.

机译：流感嗜血杆菌对哌拉西林-他唑巴坦组合的敏感性：解释性标准和标准化测试的质量控制限制。

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摘要

In vitro studies evaluated methods for testing the susceptibility of Haemophilus influenzae to piperacillin-tazobactam combinations. Ampicillin-resistant beta-lactamase-nonproducing strains of H. influenzae may be presumed to be relatively resistant to combinations of piperacillin-tazobactam, even though they frequently appear to be susceptible by disk diffusion methods. Other ampicillin-resistant or -susceptible strains were predictably susceptible; i.e., 130 such strains gave zones of inhibition > or = 26 mm in diameter, and MICs for these strains were < or = 0.125/4.0 micrograms/ml (< or = 1.0/0.12 micrograms/ml when an 8:1 ratio was tested). A resistant category has yet to be defined. For quality control purposes, H. influenzae ATCC 49247 should give zones of inhibition 32 to 38 mm in diameter, and broth microdilution MICs should be 0.12/4.0 to 0.5/4.0 micrograms/ml.
机译：体外研究评估了测试流感嗜血杆菌对哌拉西林-他唑巴坦组合的敏感性的方法。氨苄青霉素抗性β-内酰胺酶非生产性流感嗜血杆菌菌株可能被推定对哌拉西林-他唑巴坦的组合具有相对抗性，即使它们似乎经常受到圆盘扩散法的影响。其他对氨苄西林耐药或易感的菌株是可预见的。也就是说，有130个此类菌株的抑菌圈直径大于或等于26毫米，而这些菌株的MIC小于或等于0.125 / 4.0微克/毫升（当测试8：1的比例时，小于或等于1.0 / 0.12微克/毫升）。尚未定义抗性类别。出于质量控制的目的，流感嗜血杆菌ATCC 49247的抑菌圈直径应为32至38毫米，肉汤微量稀释MIC应当为0.12 / 4.0至0.5 / 4.0微克/毫升。

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