Detection of JC Virus in Cerebrospinal Fluid (CSF) Samples from Patients with Progressive Multifocal Leukoencephalopathy but Not in CSF Samples from Patients with Herpes Simplex Encephalitis, Enteroviral Meningitis, or Multiple Sclerosis

G. Bogdanovic; P. Priftakis; A.-L. Hammarin; M. S?derstr?m; A. Samuelson; I. Lewensohn-Fuchs; T. Dalianis

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Detection of JC Virus in Cerebrospinal Fluid (CSF) Samples from Patients with Progressive Multifocal Leukoencephalopathy but Not in CSF Samples from Patients with Herpes Simplex Encephalitis, Enteroviral Meningitis, or Multiple Sclerosis

机译：进行性多灶性白质脑病患者的脑脊液（CSF）样本中JC病毒的检测，但单纯疱疹性脑炎，肠病毒性脑膜炎或多发性硬化症患者的CSF样本中未检测到JC病毒

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JC virus (JCV) DNA was detected in cerebrospinal fluid (CSF) samples from patients with progressive multifocal leukoencephalopathy (PML) but not in CSF samples from patients with herpes simplex encephalitis, enteroviral meningitis, or multiple sclerosis. This suggests that inflammatory processes in the brain do not necessarily reactivate JCV, which further supports the proposal that the presence of JCV DNA in the CSF is diagnostic for PML.

机译：在进行性多灶性白质脑病（PML）患者的脑脊液（CSF）样本中检测到JC病毒（JCV）DNA，但在单纯疱疹性脑炎，肠病毒性脑膜炎或多发性硬化症患者的CSF样本中未检测到。这表明大脑中的炎症过程不一定会重新激活JCV，这进一步支持了CSF中JCV DNA的存在可以诊断PML的建议。

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《Journal of Clinical Microbiology》 |1998年第4期|共2页
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G. Bogdanovic; P. Priftakis; A.-L. Hammarin; M. S?derstr?m; A. Samuelson; I. Lewensohn-Fuchs; T. Dalianis;
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中图分类医学微生物学（病原细菌学、病原微生物学）;
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机译：渐进式多焦白血病病变性能与JC病毒聚合酶链反应导致纳莱普治疗的多发性硬化症患者的脑脊液
2. Polyoma virus JC DNA detection by polymerase chain reaction in CSF of HIV infected patients with suspected progressive multifocal leukoencephalopathy. [J] . Giri JA, Gregoresky J, Silguero P, American clinical laboratory . 2001,第9期

机译：通过聚合酶链反应检测疑似进行性多灶性白质脑病的HIV感染患者的脑脊液中多瘤病毒JC DNA的检测。
3. Detection of CSF-specific oligoclonal antibodies to recombinant JC virus VP1 in patients with progressive multifocal leukoencephalopathy. [J] . Sindic CJ, Trebst C, Van Antwerpen MP, Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology . 1997,第1a2期

机译：进行性多灶性白质脑病患者中针对重组JC病毒VP1的CSF特异性寡克隆抗体的检测。
4. Optical analysis of suspended particles in the cerebrospinal fluid obtained by puncture from patients diagnosed with the disorders of cerebrospinal fluid (CSF) circulation [C] . Waldemar Staron, Leszek Herbowski, Henryk Gurgul Polish-Czech-Slovak Optical Conference on Wave and Quantum Aspects of Contemporary Optics . 2007

机译：通过脑脊液（CSF）循环紊乱的患者穿刺脑脊液中悬浮颗粒的光学分析
5. gammadelta T cells derived from peripheral blood and cerebrospinal fluid of multiple sclerosis patients: Cytotoxic mechanisms, inhibitory natural killer cell receptors, and protein analysis. [D] . Green, Melanie Leslie Dawn. 2005

机译：多发性硬化症患者外周血和脑脊液中产生的γT细胞：细胞毒性机制，抑制性自然杀伤细胞受体和蛋白质分析。
6. Note: Detection of JC Virus in Cerebrospinal Fluid (CSF) Samples from Patients with Progressive Multifocal Leukoencephalopathy but Not in CSF Samples from Patients with Herpes Simplex Encephalitis Enteroviral Meningitis or Multiple Sclerosis [O] . G. Bogdanovic, P. Priftakis, A.-L. Hammarin, 1998

机译：注意：在进行性多灶性白质脑病患者的脑脊液（CSF）样本中检测到JC病毒但在单纯疱疹性脑炎肠病毒性脑膜炎或多发性硬化症患者的CSF样本中未检测到JC病毒
7. Detection of JC Virus in Cerebrospinal Fluid (CSF) Samples from Patients with Progressive Multifocal Leukoencephalopathy but Not in CSF Samples from Patients with Herpes Simplex Encephalitis, Enteroviral Meningitis, or Multiple Sclerosis [O] . G. Bogdanovic, P. Priftakis, A.-L. Hammarin, 1998

机译：检测脑脊液（CSF）患者患者的脑脊液（CSF）样品中的JC病毒，但在单纯疱疹脑炎，肠道病毒性脑膜炎或多发性硬化症中的CSF样本中没有CSF样品

Detection of JC Virus in Cerebrospinal Fluid (CSF) Samples from Patients with Progressive Multifocal Leukoencephalopathy but Not in CSF Samples from Patients with Herpes Simplex Encephalitis, Enteroviral Meningitis, or Multiple Sclerosis

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