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首页> 外文期刊>Journal of Clinical Microbiology >Evaluation of a new latex agglutination method for detection of antibody to herpes simplex virus.
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Evaluation of a new latex agglutination method for detection of antibody to herpes simplex virus.

机译:评价一种新的乳胶凝集方法,以检测抗单纯疱疹病毒的抗体。

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A new latex agglutination (LA) test (Wampole Laboratories, Cranbury, N.J.) for detection of antibody to herpes simplex virus was compared with a reference complement fixation (CF) method in a premarket evaluation. Of 102 serum samples tested, 19 were LA negative and CF negative, 79 were LA positive and CF positive, and 4 were LA positive and CF negative. An enzyme immunoassay (M. A. Bioproducts, Walkersville, Md.) performed on the four LA-positive and CF-negative serum samples agreed with LA in all cases. Most LA titers were two to four doubling dilutions higher than CF titers. We conclude that this new LA test is a rapid, sensitive, and simple method for documentation of past infection with herpes simplex virus.
机译:在上市前评估中,将用于检测单纯疱疹病毒抗体的新乳胶凝集(LA)测试(Wampole Laboratories,Cranbury,N.J。)与参考补体固定(CF)方法进行了比较。在测试的102个血清样本中,LA阴性和CF阴性19个,LA阳性和CF阳性79个,LA阳性和CF阴性4个。在所有情况下,均对与LA一致的四个LA阳性和CF阴性血清样品进行酶免疫测定(M. A. Bioproducts,Walkersville,马里兰)。大多数LA滴度比CF滴度高2到4倍。我们得出结论,这项新的LA测试是一种快速,灵敏且简单的方法,可用于记录过去单纯疱疹病毒感染的情况。

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