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首页> 外文期刊>Journal of Clinical Microbiology >Utility of Paired BACTEC MYCO/F LYTIC Blood Culture Vials for Detection of Bacteremia, Mycobacteremia, and Fungemia
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Utility of Paired BACTEC MYCO/F LYTIC Blood Culture Vials for Detection of Bacteremia, Mycobacteremia, and Fungemia

机译：配对的BACTEC MYCO / F LYTIC血液培养瓶可用于检测细菌血症，分枝杆菌血症和真菌病

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In previous bloodstream infection studies in Malawi, we inoculated blood from a single venesection into a single BACTEC MYCO/F LYTIC (MFL) vial. Inoculation of one vial, however, would be expected to reduce the sensitivity of bloodstream pathogen detection with MFL vials. To ascertain the degree of this loss of sensitivity, blood was drawn from each of 228 febrile, adult inpatients in Malawi and 5 ml of each blood sample was inoculated into each of two MFL vials. Of 228 paired vials, 51 (22%) were both positive, 172 (75%) were both negative, and 5 (3%) had discordant results. Bloodstream infection would have been detected in 11 (92%) of 12 patients with mycobacteremia and 38 (92%) of 41 patients with bacteremia had only one MFL vial been inoculated. Our study shows that a second MFL vial does not significantly increase diagnostic sensitivity.
机译：在之前在马拉维进行的血液感染研究中，我们将单个穿刺部位的血液接种到单个BACTEC MYCO / F LYTIC（MFL）小瓶中。但是，接种一个小瓶可能会降低MFL小瓶对血流病原体检测的敏感性。为了确定这种敏感性丧失的程度，从马拉维的228名发热的成年住院患者中抽出血液，并将5 ml的血液样本分别接种到两个MFL小瓶中。在228个配对的小瓶中，有51个（22％）均为阳性，有172个（75％）均为阴性，有5个（3％）的结果不一致。如果只接种了一个MFL小瓶，则在12例分枝杆菌血症患者中有11例（92％）可以检测到血流感染，而41例菌血症患者中38例（92％）可以检测到。我们的研究表明，第二个MFL小瓶不会显着提高诊断灵敏度。

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