Performance of the OraQuick Rapid Antibody Test for Diagnosis of Human Immunodeficiency Virus Type 1 Infection in Patients with Various Levels of Exposure to Highly Active Antiretroviral Therapy

Robert J. OConnell; Teresa M. Merritt; Jennifer A. Malia; Thomas C. VanCott; Matthew J. Dolan; Hassan Zahwa

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Performance of the OraQuick Rapid Antibody Test for Diagnosis of Human Immunodeficiency Virus Type 1 Infection in Patients with Various Levels of Exposure to Highly Active Antiretroviral Therapy

机译：OraQuick快速抗体测试对不同水平的高效抗逆转录病毒治疗患者的人免疫缺陷病毒1型感染的诊断性能

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With oral mucosal transudate and serum samples from 101 human immunodeficiency virus type 1 (HIV-1)-infected subjects and 100 HIV-1-negative volunteers, the OraQuick HIV-1 test demonstrated 100% specificity and 96% sensitivity. Four false-negative subjects, who were characterized by early initiation of effective antiretroviral therapy, demonstrated waning serum anti-gp41 titers and Western blot band intensities.

机译：OraQuick HIV-1测试对101位感染了人类免疫缺陷病毒1型（HIV-1）的受试者和100位HIV-1阴性志愿者的口腔粘膜渗出液和血清样本进行了测试，结果显示，OraQuick HIV-1测试的特异性为100％，敏感性为96％。以早期开始有效的抗逆转录病毒治疗为特征的四名假阴性受试者表现出血清抗gp41滴度和Western印迹带强度下降。

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《Journal of Clinical Microbiology》 |2003年第5期|共3页
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Robert J. OConnell; Teresa M. Merritt; Jennifer A. Malia; Thomas C. VanCott; Matthew J. Dolan; Hassan Zahwa;
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中图分类医学微生物学（病原细菌学、病原微生物学）;
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1. Response to Immunization With Measles, Tetanus, and Haemophilus influenzae Type b Vaccines in Children Who Have Human Immunodeficiency Virus Type 1 Infection and Are Treated With Highly Active Antiretroviral Therapy [J] . Ann J. Melvin, Kathleen M. Mohan Pediatrics: Official Publication of the American Academy of Pediatrics . 2003,第6期

机译：患有麻疹，破伤风和流感嗜血杆菌b型疫苗的免疫接种对患有人类免疫缺陷病毒1型感染并用高效抗逆转录病毒疗法治疗的儿童的反应
2. Predictors of plasma human immunodeficiency virus type 1 RNA control after discontinuation of highly active antiretroviral therapy initiated at acute infection combined with structured treatment interruptions and immune-based therapies. [J] . Lafeuillade A, Poggi C, Hittinger G, The Journal of Infectious Diseases . 2003,第10期

机译：急性感染引发的高活性抗逆转录病毒治疗终止后，结合结构化治疗中断和基于免疫的治疗，可预测血浆人免疫缺陷病毒1型RNA的控制情况。
3. Frequency and diversity of human immunodeficiency virus type 1 mutations associated with antiretroviral resistance among patients from Southern Brazil failing highly active antiretroviral therapy (HAART) [J] . Figueiredo SaadFlavia, Kaminami MorimotoHelena, WiechmannSusana Lilian, International journal of molecular medicine . 2010,第4期

机译：在巴西南部无法进行高效抗逆转录病毒治疗（HAART）的患者中，与抗逆转录病毒耐药相关的人类免疫缺陷病毒1型突变的频率和多样性
4. Simultaneous extraction of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) RNA with the M1000 apparatus does not impair the measurement of the viral load of both viruses when tested by using the LCx PCR system [C] . T. Bourlet, S. Thamm, S. Pillet, European Congress of Virology . 2004

机译：通过使用LCX PCR系统测试，同时提取人免疫缺陷病毒类型1（HIV-1）和丙型肝炎病毒（HCV）RNA，不会损害两种病毒的病毒载量的测量
5. Characterization of the human immunodeficiency virus type 1-specific humoral immune response during highly active antiretroviral therapy. [D] . Morris, Mary Kathleen. 2000

机译：高免疫活性抗逆转录病毒治疗过程中人类免疫缺陷病毒1型特异性体液免疫反应的特征。
6. Performance of the OraQuick Rapid Antibody Test for Diagnosis of Human Immunodeficiency Virus Type 1 Infection in Patients with Various Levels of Exposure to Highly Active Antiretroviral Therapy [O] . Robert J. OConnell, Teresa M. Merritt, Jennifer A. Malia, 2003

机译：OraQuick快速抗体测试对不同水平的高效抗逆转录病毒治疗患者的人类免疫缺陷病毒1型感染的诊断性能
7. Performance of the OraQuick Rapid Antibody Test for Diagnosis of Human Immunodeficiency Virus Type 1 Infection in Patients with Various Levels of Exposure to Highly Active Antiretroviral Therapy [O] . O'Connell, Robert J., Merritt, Teresa M., Malia, Jennifer A., 2003

机译：OraQuick快速抗体测试对不同水平的高效抗逆转录病毒治疗患者的人类免疫缺陷病毒1型感染的诊断性能
8. Quantitative Relationship of Circulating p24 Antigen with Human ImmunodeficiencyVirus (HIV) RNA and Specific Antibody in HIV-Infected Subjects Receiving Antiretroviral Therapy [R] . Brown, A. E., Vahey, M. T., Zhou, S. Y., 1995

机译：接受抗逆转录病毒治疗的HIV感染者循环p24抗原与人类免疫缺陷病毒（HIV）RNa和特异性抗体的定量关系

Performance of the OraQuick Rapid Antibody Test for Diagnosis of Human Immunodeficiency Virus Type 1 Infection in Patients with Various Levels of Exposure to Highly Active Antiretroviral Therapy

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